TADA3L Antikörper (Middle Region)

Produktnummer ABIN182375

Produktdetails anti-TADA3L Antikörper

Target: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TADA3L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ASVEPYCADI TSEEVRTLEE LLKPPEDEAE HYKIPPLGKH YSQRWAQEDL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TADA3L. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TADA3L

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 432 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TADA3L

Target: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Andere Bezeichnung: TADA3L (TADA3 Produkte)

Synonyme: ADA3 antikoerper, NGG1 antikoerper, STAF54 antikoerper, TADA3L antikoerper, hADA3 antikoerper, Tada3l antikoerper, 1110004B19Rik antikoerper, AI987856 antikoerper, fa03f04 antikoerper, tada3 antikoerper, wu:fa03f04 antikoerper, zgc:63596 antikoerper, ada3 antikoerper, ada3-A antikoerper, ngg1 antikoerper, tada3l antikoerper, tada3l-a antikoerper, ada3-B antikoerper, tada3l-B antikoerper, transcriptional adaptor 3 antikoerper, transcriptional adapter 3 pseudogene antikoerper, transcriptional adaptor 3 (NGG1 homolog, yeast)-like antikoerper, transcriptional adaptor 3 L homeolog antikoerper, transcriptional adaptor 3 S homeolog antikoerper, TADA3 antikoerper, Tada3 antikoerper, LOC732883 antikoerper, LOC100061462 antikoerper, tada3 antikoerper, LOC100619707 antikoerper, tada3l antikoerper, tada3.L antikoerper, tada3.S antikoerper

Hintergrund: Adaptor proteins are usually required for transcriptional activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter.TADA3L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.
Alias Symbols: ADA3, FLJ20221, FLJ21329, hADA3, NGG1, TADA3L
Protein Interaction Partner: HEXIM2, CCDC101, CCNC, TP53, USP22, KDM1A, TADA2A, KAT2B, TAF5L, NUP205, SUPT3H, YEATS2, MBIP, WDR5, MAP3K7, DR1, PIAS4, MAGEH1, ING5, XRCC6, SUMO2, SREBF1, TXNRD2, NR1I2, RARA, ESR1, AR, KAT2A, EP300, CTNNB1, ANKRD12, ATXN7, TAF10, FAM107B, ADPGK, HSPA8,
Protein Size: 432

Molekulargewicht: 49 kDa

Gen-ID: 10474

NCBI Accession: NM_006354, NP_006345

UniProt: O75528

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway