Macrophage Mannose Receptor 1 Antikörper (Biotin)

Produktnummer ABIN181884

Produktdetails anti-Macrophage Mannose Receptor 1 Antikörper (Biotin)

Target: Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Macrophage Mannose Receptor 1 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Spezifität: This antibody recognises the mannose receptor, a 175 kDa type 1 membrane protein that is also known as CD206. Clone MR5D3 has been reported to be non-inhibitory for the binding of the mannose receptor to carbohydrate ligands.

Aufreinigung: Affinity chromatography on Protein G

Immunogen: Chimaeric CRD4-7-Fc protein. Spleen cells from immunised Fischer rats were fused with cells of the Y3 myeloma cell line.

Klon: MR5D3

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL, The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-Macrophage Mannose Receptor 1 Antikörper (Biotin) (ABIN181884)

Terminel, Bassil, Rau, Trevino, Ruiz, Alaniz, Hook: "Morphine-induced changes in the function of microglia and macrophages after acute spinal cord injury." in: BMC neuroscience, Vol. 23, Issue 1, pp. 58, (2022) (PubMed).

Details zu Macrophage Mannose Receptor 1

Target: Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))

Andere Bezeichnung: CD206 / MRC1 (MRC1 Produkte)

Synonyme: CD206 antikoerper, CLEC13D antikoerper, CLEC13DL antikoerper, MMR antikoerper, MRC1L1 antikoerper, bA541I19.1 antikoerper, AW259686 antikoerper, MR antikoerper, mrc1 antikoerper, MGC86525 antikoerper, MRC1 antikoerper, MRC1L-A antikoerper, mannose receptor C-type 1 antikoerper, mannose receptor, C type 1 antikoerper, mannose receptor C-type 1 L homeolog antikoerper, mediator of replication checkpoint 1 antikoerper, MRC1 antikoerper, Mrc1 antikoerper, mrc1.L antikoerper, mrc1 antikoerper

Hintergrund: CD206 is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.Synonyms: C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, CLEC13D, CLEC13DL, MRC1L1, Macrophage mannose receptor, Macrophage mannose receptor 1-like protein 1

Gen-ID: 17533

NCBI Accession: NP_032651

UniProt: Q61830