CD11c Antikörper (Internal Region)

Produktnummer ABIN181257

Produktdetails anti-CD11c Antikörper

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD11c Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody recognises Integrin Alpha X, Family: Integrin, Subfamily: not assigned-Integrin.

Kreuzreaktivität (Details): Species reactivity (expected):Gorilla, GibbonSpecies reactivity (tested):Human

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic 14 amino acid peptide from internal region of Human ITGAX / CD11c.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Embedded Tissues (20 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Details zu CD11c

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Andere Bezeichnung: CD11c (ITGAX Produkte)

Synonyme: CD11C antikoerper, SLEB6 antikoerper, RGD1561123 antikoerper, AI449405 antikoerper, Cd11c antikoerper, Cr4 antikoerper, N418 antikoerper, integrin subunit alpha X antikoerper, integrin alpha X antikoerper, ITGAX antikoerper, Itgax antikoerper

Hintergrund: CD11c / ITGAX encodes the integrin alpha X chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 seems to broadly overlap the properties of the alpha M beta 2 integrin in adherence of neutrophils and monocytes to stimulated endothelium, and the phagocytosis of complement coated particles.Synonyms: CD11 antigen-like family member C, ITGAX, Integrin alpha-X, Leu M5, Leukocyte adhesion glycoprotein p150 95 alpha chain, Leukocyte adhesion receptor p150 95

Gen-ID: 3687

NCBI Accession: NP_000878

UniProt: P20702

Pathways: Komplementsystem, Activated T Cell Proliferation, Integrin Complex