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CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) (AA 202-216) Antikörper

Details zu Produkt Nr. ABIN181099, Anbieter: Anmelden zum Anzeigen
Antigen
  • CD79A
  • Ig-alpha
  • Iga
  • Igalpha
  • Ly-54
  • Ly54
  • mb-1
  • IGA
  • MB-1
  • IG-alpha
Epitop
AA 202-216
49
38
23
16
15
15
10
9
5
4
3
3
3
3
2
2
1
1
1
1
1
1
1
Reaktivität
Huhn, Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Affe, Maus, Schwein, Kaninchen, Ratte (Rattus)
252
81
42
38
37
31
29
29
26
20
16
9
6
3
3
3
3
3
3
2
Wirt
Maus
169
112
4
1
Klonalität (Klon)
Monoklonal ()
Konjugat
Unkonjugiert
20
19
13
13
7
5
2
2
2
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
131
121
69
62
53
23
23
19
6
4
4
4
3
2
2
1
1
1
1
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Immunogen Synthetic peptide corresponding to 202-216 amino acid sequence of Human mb-1. Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cellline. Genename: CD79a
Klon HM57
Isotyp IgG1
Spezifität This antibody recognizes an epitope within the cytoplasmic domain of CD79a. CD79a, also known as mb-1, is a 45 kDa protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells.
Produktmerkmale Synonyms: IGA, MB1, B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain,MB-1 membrane glycoprotein, Surface IgM-associated protein, Membrane-boundimmunoglobulin-associated protein
Reinigung Affinity Chromatography on Protein G
Andere Bezeichnung CD79a (CD79A Antibody Abstract)
Hintergrund The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin.Synonyms: B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain, IGA, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein
Gen-ID 973
UniProt P11912
Forschungsgebiet Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells
Applikationshinweise Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: 1/100-1/500, This product requires antigenretrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. Recommended Positive Control: Human tonsilFlow Cytometry: Use 10 μL of 1/50-1/100 diluted CD79a antibody to label 1x10^6 cells in 100μL (Membrane permeabilisation is required). Has been reported to work in Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1.0 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Haltbarkeit 12 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) (AA 202-216) Antikörper (ABIN181099) anti-CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) (AA 202-216) antibody
Allgemeine Veröffentlichungen Jones, Cordell, Beyers et al.: "Detection of T and B cells in many animal species using cross-reactive anti-peptide antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 150, Issue 12, pp. 5429-35, 1993 (PubMed).

Mason, Cordell, Tse et al.: "The IgM-associated protein mb-1 as a marker of normal and neoplastic B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 11, pp. 2474-82, 1991 (PubMed).