CLEC10A Antikörper (Biotin)

Produktnummer ABIN181063

Produktdetails anti-CLEC10A Antikörper (Biotin)

Target: CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CLEC10A Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Spezifität: This antibody recognises the CD301 cell surface protein. In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Clone ER-MP23 is reported to block the function of murine CD301. The antibody binds both MGL1 and MGL2 homologues.

Produktmerkmale: Synonyms: CLECSF13, CLECSF14, HML, C-type lectin domain family 10 member A, C-type lectinsuperfamily member 14, Macrophage lectin 2

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Balb/c macrophage precursor cell hybrids. Cells from immunised rats were fused with cells of the rat Y3-Ag1. 2. 3 myeloma cell line.

Klon: ER-MP23

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Use 10 μL of Neat-1/10 diluted antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Referenzen für anti-CLEC10A Antikörper (Biotin) (ABIN181063)

Lederle, Hartenstein, Meides, Kunzelmann, Werb, Angel, Mueller: "MMP13 as a stromal mediator in controlling persistent angiogenesis in skin carcinoma." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1175-84, (2010) (PubMed).

Details zu CLEC10A

Target: CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))

Andere Bezeichnung: CD301 / CLEC10A (CLEC10A Produkte)

Synonyme: CLEC10A antikoerper, CD301 antikoerper, CLECSF13 antikoerper, CLECSF14 antikoerper, HML antikoerper, HML2 antikoerper, MGL antikoerper, CD301a antikoerper, M-ASGP-BP-1 antikoerper, Mgl antikoerper, Mgl1 antikoerper, Mgll antikoerper, C-type lectin domain family 10 member A antikoerper, C-type lectin domain containing 10A antikoerper, C-type lectin domain family 10, member A antikoerper, LOC607405 antikoerper, CLEC10A antikoerper, Clec10a antikoerper

Hintergrund: In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Expression of CD301 is induced by alternative (i.e. IL-4/IL-13 mediated) activation of macrophages and dendritic cells, but not all CD301 positive cells are necessarily IL-4/IL-13 stimulated.Synonyms: C-type lectin domain family 10 member A, C-type lectin superfamily member 14, CLECSF13, CLECSF14, HML, Macrophage lectin 2

Gen-ID: 10462

UniProt: Q8IUN9