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Substance P Antikörper

Antigen

Substance P

Synonyme NK2, NPK, NKNA, TAC2, Hs.2563, SP, NK1, NK-1, Nkna, PPT-A, MGC151458, 4930528L02Rik
Klonalität Monoklonal (NC1-34)
Wirt
Alternativen

Ratte

Reaktivität
Alternativen

Human

Applikation
Alternativen Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunfluoreszenz (IF), Immunhistochemie (Paraffinschnitte) (IHC (p))
Produktnummer ABIN181043
Menge 0.1 ml
Preis 430,00 €   Zzgl. Versandkosten €40,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Produktmerkmale Synonyms: Substance-P
Gen-ID 6863
Swiss-Prot P20366
Immunogen Substance P conjugated to Bovine Serum Albumin. Spleen cells from immunised Wistar ratwere fused with cells of the NS1/1-Ag 4-1 myeloma cell line.
Format Supernatant
Isotyp IgG2a  (Passende Sekundärantikörper)
Klon NC1-34
Beschreibung Substance P is known to have a role in several physiologic activities such as paintransmission, the vomiting reflex, salivary secretion and smooth muscle contraction. 5%reactivity is observed with eledoisin. It does not react with Leu or Met-enkephalin,somatostatin or betaendorphin.
Spezifität This antibody recognizes the COOH terminal end of substance P, a short polypeptideneurotransmitter that regulates the excitability of dorsal horn nociceptive neurons. 5 % reactivity is observed with eledoisin. It does not react with Leu or Met-enkephalin,somatostatin or beta-endorphin.

Anwendungen

Applikationshinweise Immunohistochemistry on frozen sections: 1/100 - 1/200. Immunohistochemistry on paraffin sections: 1/100 - 1/200, Pre-treatment is not required. Immunofluorescence: This antibody has been used for the localisation of substance P intissue sections by immunofluorescence and PAP staining in nervous systems ofexperimental animals and man. Please refer to the Cuello references listed below. It hasalso been successfully applied in archive post-mortem tissues of the human brain, see Maiand Pioro references. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Buffer 0.09% Thiomersal
Lagerung Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Forschungsgebiet Neurologie, Zell-/Gewebemarker
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Substance P", Typ "Antikörper" finden
Wirte Kaninchen (39), Maus (9), Meerschweinchen (4), Ratte (2)
Reaktivitäten Human (39), Ratte (Rattus) (26), Maus (22), Meerschweinchen (17), Rind (Kuh) (16), Kaninchen (16), Pferd (15), Schaf (15), Säugetiere (2), Huhn (1), Fisch (1), Affe (1), Schwein (1)
Applikationen Immunfluoreszenz (IF) (31), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (20), Durchflusszytometrie (FACS) (19), Immunhistochemie (Paraffinschnitte) (IHC (p)) (16), ELISA (8), Immunhistochemie (IHC) (8), Enzyme Immunoassay (EIA) (4), Western Blot (WB) (4), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunpräzipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Radioimmunoassay (RIA) (1)
Konjugate Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitope AA 4-11 (2)