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Antikörper
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anti-Interleukin 17A (IL17A) Antikörper (Biotin)
Interleukin 17A (IL17A) Antikörper (Biotin)
| Antigen |
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| Synonyme |
IL17, CTLA8, IL-17, IL-17A, Il17, Ctla8, Ctla-8, IL17F, IL17A, ChIL-17 |
| Klonalität |
Monoklonal (TC11-8H4) |
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Wirt
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Reaktivität
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Konjugat
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Applikation
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Durchflusszytometrie (FACS) (57), Western Blot (WB) (31), ELISA (23), Enzyme Immunoassay (EIA) (22), Neutralisierung (Neut) (22), Intrazelluläre Durchflusszytometrie (ICFC) (18), ELISA (Detektionsantikörper) (12), ELISPOT (11), ELISA (Fangantikörper) (8), Immunhistochemie (Paraffinschnitte) (IHC (p)) (7), Funktionale Studien (Func) (5), ELISPOT (Fangantikörper) (2), ELISPOT (Detektionsantikörper) (2), Immunfluoreszenz (IF) (2), Immunhistochemie (IHC) (2), Dot Blot (Dot) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1)
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| Produktnummer |
ABIN181031 |
| Menge |
0.5 mg (0.5 mg/ml) |
| Preis |
490,00 € Zzgl. Versandkosten €40,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: IL-17A, IL17, IL-17, CTLA8, CTLA-8, Cytotoxic T-lymphocyte-associated antigen 8
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Weitere Bezeichnung
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Interleukin-17A (IL17A)
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Swiss-Prot
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Q62386
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Isotyp
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IgG1
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Klon
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TC11-8H4
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Beschreibung
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IL17, also known as CTLA8, is a T cell derived hematopoietic cytokine. It was originallycloned from a T cell hybridoma produced by fusion of a mouse cytotoxic T cell clone and arat T lymphoma. IL17 exhibits multiple biological activities on a variety of cells including: the induction of IL6, IL8 and GCSF production in fibroblasts, the enhancement of surfaceexpression of ICAM 1 in fibroblasts, activation of NF kappaB and costimulation of T cellproliferation. IL17 is an approximately 16 kDa polypeptide of 136 amino acids. Theprecursor form of IL17 consists of 155 amino acids. To generate the mature IL17 (136 aminoacids), the precursor cleaves a 19 amino acid signal peptide. Human IL17 showsapproximately 62. 5% amino acid homology to mouse IL17 and 58% amino acid homologyto rat IL17.
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Spezifität
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This antibody reacts to Interleukin 17. Species: Mouse. Others not tested.
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Applikationshinweise
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ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Konzentration
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0.5 mg/ml
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Buffer
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PBS containing 0.09% Sodium azideLabel: Biotin
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Lagerung
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Forschungsgebiet
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Zytokine, Rezeptoren, Inflammation, Immunologie, Virologie, Krebs
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Interleukin 17A (IL17A)", Typ "Antikörper" finden
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Wirte
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Maus (88), Ratte (26), Kaninchen (17), Ziege (5), Huhn (1)
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Reaktivitäten
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Human (105), Maus (33), Ratte (Rattus) (3)
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Applikationen
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Durchflusszytometrie (FACS) (57), Western Blot (WB) (31), ELISA (23), Enzyme Immunoassay (EIA) (22), Neutralisierung (Neut) (22), Intrazelluläre Durchflusszytometrie (ICFC) (18), ELISA (Detektionsantikörper) (12), ELISPOT (11), ELISA (Fangantikörper) (8), Immunhistochemie (Paraffinschnitte) (IHC (p)) (7), Funktionale Studien (Func) (5), ELISPOT (Fangantikörper) (2), ELISPOT (Detektionsantikörper) (2), Immunfluoreszenz (IF) (2), Immunhistochemie (IHC) (2), Dot Blot (Dot) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1)
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Konjugate
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Biotin (23), Alexa Fluor 647 (9), HRP (8), FITC (7), PE (7), PerCP,Cy5.5 (6), Alexa Fluor 488 (5), Pacific Blue (4), APC (1)
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Epitope
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N-Term (2), AA 20-155 (1), Center (1)
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Alternativen 
