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Claudin 6 (CLDN6) Antikörper

Antigen

Claudin 6 (CLDN6)

Synonyme AL024037, cldn6, MGC81720, CLDN6
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Applikation
Alternativen Immunhistochemie (IHC), Western Blot (WB)
Produktnummer ABIN180218
Menge 100 µg
Preis 324,00 €   Zzgl. Versandkosten €40,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 10 bis 15 Werktagen

Produktbeschreibung

Weitere Bezeichnung Claudin-6 (C)
Immunogen Synthetic peptide of part of C terminal of Mouse Claudin-6 (SRGPSEYPTKNYV) Purification: Purified with antigen peptide
Isotyp IgG  (Passende Sekundärantikörper)
Beschreibung The tight junction is identified as a belt-like region in which two lipid-apposing membranes lie close together (tight junction strands). Tight junction strands of the adjacent cells form tightly connected pairs. The proteins involved in the formation of tight junctions are divided into two categories: 1) integral membrane proteins, such as occludin, claudin and junctional adhesion molecule, JAM and 2) peripheral membrane proteins (cytoplasmic plaque proteins), MAGUK (membrane-associated guanylate kinase) homologue proteins, such as ZO-1, 2, 3, cingulin, symplekin, 19B1, and AF-6. In human, the claudin superfamily consists of at least 18 members, which are involved on paracellular transport as structural and functional components of tight junction. Claudins are directly associated with ZO-1, 2 and 3 and indirectly with AF-6 and cingulin.
Spezifität Claudin-6 specific. No crossreactivities with Claudin-1, -2, -3, -4, -5, -7, -8, -12, and -15 (This confirmed by western blotting using each transfectants)

Anwendungen

Applikationshinweise This antibody can be stained in frozen tissues by several Immunohistochemical techniques such as immunofluoroscent method. The optimal dilution is about 5 ug/mL, however, the dilution rate should be optimized by each laboratories.:This antibody can be used for western blotting in concentration of about 1ug/mL.
Reinigung Antigen peptide
Buffer Lyophilized product from 1% BSA in PBS containing 0.05% NaN3 . Reconstitution: 1.0 mL distilled water will be added to the product, then its concentration comes to 100 ug/mL
Lagerung Lyophilized product, 5 years at 2 ­ 8 C : Solution, 2 years at ­20 C
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Claudin 6 (CLDN6)", Typ "Antikörper" finden
Wirte Kaninchen (30)
Reaktivitäten Human (28), Maus (23), Ratte (Rattus) (18), Rind (Kuh) (1), Hund (1), Pferd (1)
Applikationen Immunfluoreszenz (IF) (20), Durchflusszytometrie (FACS) (18), Western Blot (WB) (10), ELISA (6), Immunhistochemie (IHC) (3), Immunhistochemie (Paraffinschnitte) (IHC (p)) (3), Enzyme Immunoassay (EIA) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunpräzipitation (IP) (2), Dot Blot (Dot) (1), Immunoelectron Microscopy (IEM) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1)
Konjugate Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitope C-Term (1), pTyr219 (1)