MBD2 (Methylated DNA Binding Domain 2) Antikörper

Antigen: MBD2 (Methylated DNA Binding Domain 2)

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN180217

Produktbeschreibung

Immunogen: Synthetic peptide of part of C terminal of human MBD2 (TEEMDIEMDSGDEA) Purification: Purified with antigen peptide

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Methylation at CpG dinucleotides in genomic DNA is a fundamental epigenetic mechanism of gene expression control in vertebrates. Proteins with a methyl-CpG-binding domain (MBD) can bind to single methylated CpGs and ,ost of them are involved in transcription control. So far, five vertebrate MBD proteins have been described as MBD family members: BD1, MBD2, MBD3, MBD4 and MECP2.

Spezifität: No cross-reactivities with MBD3 (by western blotting)

Anwendungen

Applikationshinweise: This antibody can be used for western blotting at about 2 ug/ml.

Reinigung: Antigen peptide

Buffer: Lyophilized product from 1% BSA in PBS containing 0.05% NaN3 . Reconstitution: 1.0 ml distilled water will be added to the product, then its concentration comes to 100 ug/ml

Lagerung: Lyophilized product, 5 years at 2 ­ 8 C : Solution, 2 years at ­20 C

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-MBD2 (Methylated DNA Binding Domain 2) antibody