Interferon Regulatory Factor 3 (IRF3) Antikörper

Antigen: Interferon Regulatory Factor 3 (IRF3)

Synonyme: IRF-3, MGC91046, C920001K05Rik, MGC94729, IRF3, irf3

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunhistochemie (IHC), Western Blot (WB), Immunpräzipitation (IP)

Produktnummer: ABIN180209

Produktbeschreibung

Weitere Bezeichnung: IRF-3 (Interferon Regulatory Factor-3)

Immunogen: Synthetic peptide for a.a.137 ­ a.a.150 (EDILDELLGNMVLA) of IRF-3 Purification: Affinity Purified with synthetic peptide

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Interleukin Regulatory Factor-3 (IRF-3) is the gene coding for a regulatory factor that mediates the action of IL-1, TNFalpha and LPS. It is reported that IRF-3 controls the production of interferons and chemokines in virus infected cells, by a posttranslational mechanism that involves virus induced phosphorylation, protein dimerization, cytoplasmic to nuclear translocation and stimulation of responsive genes. Furthermore, it is reported that the chemokine RANTES, an important physiological inhibitor of HIV replication, is controlled by IRF-3 activation.

Spezifität: Confirmed by western blotting using His tag IRF-3.

Anwendungen

Applikationshinweise: This antibody can be stained in formalin fixed paraffin embedded tissues without any pre-treatment by several Immunohistochemical techniques such as Avidin Biotin Complex (ABC) Method. The optimal dilution is 1 - 5 ug/ml, however, the dilution rate should be optimized by each laboratories. This antibody can be used for western blotting at 1 ­5 ug/ml.

Reinigung: Antigen peptide

Buffer: Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1.0 ml distilled water will be added to the product, then its concentration comes to 100 ug/ml

Lagerung: Lyophilized product, 5 years at 2 ­ 8 C : Solution, 2 years at ­20 C

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Interferon Regulatory Factor 3 (IRF3) antibody