Syndecan 4 (SDC4) Antikörper

Antigen: Syndecan 4 (SDC4)

Synonyme: SYND4, MGC22217, Synd4, AA959608, AW108331, ryudocan, syndecan-4, RYUDOCA, RATRYUDOCA, SDC4, sdc4l, wu:fc47g09, amphiglycan, DKFZp469H1323

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN180206

Produktbeschreibung

Weitere Bezeichnung: Syndecan-4

Immunogen: Maltose Binding Protein (MBP) - Syndecan-4 recombinant protein Purification: Purified with Recombinant Syndecan-4

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Syndecan, a cell surface proteoglycan, is an integral membrane protein acting as a receptor for the extracellular matrix. The syndecan family of four transmembrane heparan sulfate proteoglycans binds a variety of soluble and insoluble extracellular effectors. Syndecan extracellular domains (ectodomains) can be shed intact by proteolytic cleavage of their core proteins, yielding soluble proteoglycans that retain the binding properties of their cell surface precursors. The syndecan-4 acts in conjunction with the 51 integrin to promote the formation of actin stress fibers and focal adhesions in fibronectin-adherent cells.

Spezifität: Confirmed by western blotting. Cross-Reactivities not tested

Anwendungen

Applikationshinweise: This antibody can be stained in formalin fixed paraffin embedded tissues after microwave pretreatment (10 min, 1-0mM Citrate Buffer, pH 6.0) by several Immunohistochemical techniques such as Avidin Biotin Complex (ABC) method. The optimal dilution is 2~4 ug/ml, however, the dilution rate should be optimized by each laboratories. This antibody can be used for western blotting at 1~2 ug/ml.

Reinigung: Antigen peptide

Buffer: Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1.0 ml distilled water will be added to the product, then its concentration comes to 100 ug/ml

Lagerung: Lyophilized product, 5 years at 2 ­ 8 : Solution, 2 years at ­20

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

pleural mesothelioma

MKN45 transplants into nude mouse

anti-Syndecan 4 (SDC4) antibody (Image 3)