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Antikörper
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anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) Antikörper
TIMP Metallopeptidase Inhibitor 1 (TIMP1) Antikörper
| Antigen |
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| Synonyme |
EPA, EPO, HCI, CLGI, TIMP, FLJ90373, TIMP1, TIMP-1, DKFZp468A0912 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Human (90), Ratte (Rattus) (10), Maus (7), Rind (Kuh) (5), Schaf (4), Affe (3), Pferd (2), Kaninchen (2), Frettchen (1), Hamster (1), Makake (1)
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Applikation
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Western Blot (WB) (87), Immunhistochemie (Paraffinschnitte) (IHC (p)) (43), ELISA (31), Enzyme Immunoassay (EIA) (12), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (9), Immunhistochemie (IHC) (6), Dot Blot (Dot) (2), ELISA (Detektionsantikörper) (2), Neutralisierung (Neut) (2), Blockierende Antikörper (Inhibition) (1), Durchflusszytometrie (FACS) (1), Funktionale Studien (Func) (1), Immunhistochemie (Paraformaldehyd) (IHC (pfa)) (1), Immunpräzipitation (IP) (1)
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| Produktnummer |
ABIN180201 |
| Menge |
100 µg |
| Preis |
324,00 € Zzgl. Versandkosten €40,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 10 bis 15 Werktagen |
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Weitere Bezeichnung
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TIMP-1 (T172)
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Immunogen
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The part of Synthetic peptide of TIMP-1 protein (177-188) Purification: Purified with antigen peptide
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Isotyp
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IgG (Passende Sekundärantikörper)
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Beschreibung
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Tissue inhibitor of Metalloprotinase (TIMP-1) is endogenous-specific inhibitor produced simultaneously with matrix metalloproteinase (MMP). TIMP-1 inhibits both active MMP to control degeneration of extracellular matrix (ECM) and conversion of intermediate form into active form. In addition, TIMP-1 forms complex with not only active MMP but also potential MMP. Especially, TIMP-1 binds to potential MMP-9 by affinity of C-terminal domain to one another. The degeneration of extracellular matrix is essential step in invation and metastasis of tumor cell. It is considered that tumor cell collects protease on the surface of cell and degenerates ECM in invading tissue.
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Spezifität
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Confirmed by Recombinant TIMP-1
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Applikationshinweise
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This antibody can be used for western blotting in concentration of 1~5 ug/ml.
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Reinigung
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Antigen peptide
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Buffer
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Lyophilized product from 1% BSA in PBS containing 0.05% NaN3 . Reconstitution: 1.0 ml distilled water will be added to the product (In storing, please add NaN3 to the products after reconstitution)
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Lagerung
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Lyophilized product, 5 years at 2 8 C : Solution, 2 years at 20 C
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "TIMP Metallopeptidase Inhibitor 1 (TIMP1)", Typ "Antikörper" finden
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Wirte
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Maus (56), Kaninchen (43), Ratte (2)
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Reaktivitäten
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Human (90), Ratte (Rattus) (10), Maus (7), Rind (Kuh) (5), Schaf (4), Affe (3), Pferd (2), Kaninchen (2), Frettchen (1), Hamster (1), Makake (1)
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Applikationen
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Western Blot (WB) (87), Immunhistochemie (Paraffinschnitte) (IHC (p)) (43), ELISA (31), Enzyme Immunoassay (EIA) (12), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (9), Immunhistochemie (IHC) (6), Dot Blot (Dot) (2), ELISA (Detektionsantikörper) (2), Neutralisierung (Neut) (2), Blockierende Antikörper (Inhibition) (1), Durchflusszytometrie (FACS) (1), Funktionale Studien (Func) (1), Immunhistochemie (Paraformaldehyd) (IHC (pfa)) (1), Immunpräzipitation (IP) (1)
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Konjugate
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Biotin (5)
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Epitope
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C-Term (2), N-Term (2), AA 4-202 (1), Ab-2 (1)
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Alternativen 
