IL-6 Antikörper

Antigen: IL-6

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Ratte (Rattus)

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN180180

Produktbeschreibung

Immunogen: Synthetic peptide in portion of N-terminus of Rat IL-6 Purification: Purified with antigen peptide

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Interleukin-6 (IL-6) is one of cytokines which was found as a B cell differentiation-inducing factor. In these days, IL-6 is generating a lot of attention not only from antibody-producing system but also from assorted physiologically activity such as induction in biosynthesis of acute stage protein in hepatocytes and acceleration of proliferation based on synergism with IL-3. It consistently becomes clear that IL-6 has relevance to pathologic condition. For example, it is reported that growth factor of multiple disease is IL-6, and that myeloma cell itself produces IL-6 and expresses IL-6 receptor. Further, participation of IL-6 to various inflammatory disease and autoimmune disease is suggested.

Anwendungen

Applikationshinweise: This antibody can be stained in formalin fixed paraffin embedded tissues by several Immunohistochemical techniques such as Avidin Biotin Complex (ABC) method. The optimal dilution is about 5 ug/ml, however, the dilution rate should be optimized by each laboratories.:This antibody can be used for western blotting in concentration of about 2~5 g/ml.

Reinigung: Antigen peptide

Buffer: Lyophilized product from 1% BSA in PBS containing 0.05% NaN3 . Reconstitution: 1.0 ml distilled water will be added to the product.

Lagerung: Lyophilized product, 5 years at 2 ­ 8 C : Solution, 2 years at ­20 C

Forschungsgebiet: Zytokine, Immunologie, Virologie, Inflammation, Krebs

Beschränkungen: Nur für Forschungszwecke einsetzbar