Vascular Endothelial Growth Factor (VEGF) (V-3) Antikörper

Antigen: Vascular Endothelial Growth Factor (VEGF)

Synonyme: vegf-A, VEGF, DmVEGF-1, EP1624, PVF, PVF1, PVFs, VEGF2-B, Vegf17E, Vegf17e-a, Vegf17e-b, l(1)G0146, vegf1, DmelCG7103, CG7103, DmVEGF-2, PV2, PVF2, VEGF-2, VEGF27Cb, DmelCG13780, CG13780, CG13781, CG13782, CG13783, CG31629, CG4492, DmVEGF-3, PVF3, VEGF27Ca, DmelCG34378, CG34378, vegf, LOC100033839

Epitope: V-3

Klonalität: Polyklonal

Wirt: Kaninchen

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN180159

Produktbeschreibung

Weitere Bezeichnung: VEGF (V-3)

Immunogen: Synthetic peptide for Human VEGF conjugating bovine thyroglobulin Purification: Affinity Purified with synthetic peptide

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Vascular Endothelial Cell Growth Factor (VEGF) is a homodimeric protein initially purified from media conditioned by normal bovine pituitary folliculo-stellate cells and secreted by a variety of vascularized tissues. It was subsequently found to be identical to a vascular permeability factor (VPF), which was previously identified in media conditioned by tumor cell lines based upon its ability to increase the permeability of capillary blood vessels. The reported activities of VEGF include stimulation of endothelial cell growth, angiogenesis and capillary permeability. Human VEGF is a 38.2kDa homodimeric protein consisting of two 165 amino acid polypeptide chains. VEGF is expressed in many human tumor cells, including human adenocarcinoma, human pancreatic carcinoma, human hepatocellular carcinoma, renal cell carcinoma, fibrosarcoma, HL60 promyelocytic leukemia, GS-9L glioma and U937 lymphoma cells. In normal tissues, VEGF expression has been observed in activated macrophages, keratinocytes, hepatocytes, smooth muscle cells Leydig cells, embryonic fibroblasts and bronchial and choroids plexus epithelium, renal glomerular visceral epithelium and mesangial cells.

Spezifität: Human, Rat, Mouse. This antibody does not react with Human VEGF121 Chemotactic: Inhibit migration of neutrophil (up to 6 nM) at 10 ug/ml Activity

Synonyme: vegf-A, VEGF, DmVEGF-1, EP1624, PVF, PVF1, PVFs, VEGF2-B, Vegf17E, Vegf17e-a, Vegf17e-b, l(1)G0146, vegf1, DmelCG7103, CG7103, DmVEGF-2, PV2, PVF2, VEGF-2, VEGF27Cb, DmelCG13780, CG13780, CG13781, CG13782, CG13783, CG31629, CG4492, DmVEGF-3, PVF3, VEGF27Ca, DmelCG34378, CG34378, vegf, LOC100033839

Anwendungen

Applikationshinweise: This antibody can be stained both in frozen sections and in formalin fixed paraffin embedded tissues by several Immunohistochemical techniques such as Avidin Biotin Complex (ABC) Method. The optimal dilution is 2-5 ug/ml, however, the dilution rate should be optimized by each laboratories.:This antibody can be used for western blotting in concentration of 2-5 ug/ml.

Reinigung: Antigen peptide

Buffer: Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1 ml distilled water will be added to the product

Lagerung: Lyophilized product, 5 years at 2 ­ 8 : Solution, 2 years at ­20

Forschungsgebiet: Krebs

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Human colon cancer

anti-Vascular Endothelial Growth Factor (VEGF) (V-3) antibody (Image 2)