Fatty Acid Synthase (FASN) Antikörper

Antigen: Fatty Acid Synthase (FASN)

Synonyme: FASN, FAS, fj34h12, wu:fj34h12, Cgl0836, A630082H08Rik, OA-519, SDR27X1, MGC14367, MGC15706, BcDNA:GH07626, DM_7295848, Fatty acid synthase, anon-EST:Posey235, anon-EST:Posey43, anon-WO0138581.1, DmelCG3523

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN180147

Produktbeschreibung

Weitere Bezeichnung: Fatty Acid Synthase

Immunogen: Synthetic peptide for a part of Human Fatty Acid Synthase Purification: Affinity Purified with synthetic peptide

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Animal fatty acid synthase (FAS) is a homodimer protein, which synthesizes long-chain fatty acids and is rich in liver, brain, breast and lung. However, the precise cellular localization of FAS in human tissue has not been elucidated. Immunohistochemistry with this antibody to human FAS revealed that in adult human tissues FAS is distributed mainly in cells with high lipid metabolism, in hormone-sensitive cells, and in a subset of epithelial cells of duodenum and stomach, colon absorptive cells, cerebral neurons, basket cells of cerebellum, deciduas, uroepithelium and epidermis. In fetal cells at 20 weeks of gestation, FAS was mainly present in proliferative epithelial cells of the digestive and respiratory systems, proximal renal tubules, adrenocortical cells, and mesenchymal and hematolymphoid cells.

Spezifität: Human FAS specific. crossreactivities withivity with rat and mice are not tested.

Synonyme: FASN, FAS, fj34h12, wu:fj34h12, Cgl0836, A630082H08Rik, OA-519, SDR27X1, MGC14367, MGC15706, BcDNA:GH07626, DM_7295848, Fatty acid synthase, anon-EST:Posey235, anon-EST:Posey43, anon-WO0138581.1, DmelCG3523

Anwendungen

Applikationshinweise: This antibody can be stained in formalin fixed paraffin embedded tissues. The optimal dilution is 2 ·`5 ug/ml, however, the dilution rate should be optimized by each laboratories.:This antibody can be used for western blotting in concentration of 2 - 5 ug/ml.

Reinigung: Antigen peptide

Buffer: Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1 ml distilled water will be added to the product

Lagerung: Lyophilized product, 5 years at 2 ­ 8 C : Solution, 2 years at ­20 C

Forschungsgebiet: Krebs

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Human breast cancer

anti-Fatty Acid Synthase (FASN) antibody (Image 2)

Publikationen

Publikationen: Lo Celso, Berta, Braun et al.: "Characterization of bipotential epidermal progenitors derived from human sebaceous gland: contrasting roles of c-Myc and beta-catenin." in: Stem cells (Dayton, Ohio), Vol. 26, Issue 5, pp. 1241-52, 2008 (PubMed).