Endothelin 1 (EDN1) (AA 22-38) Antikörper

Antigen: Endothelin 1 (EDN1)

Synonyme: ET1, HDLCQ7, EDN1, EDN, ET-1, Edn1, et1, et-1, preproET, Et1, fb14d01, wu:fb14d01, PPET1, PPET-1

Epitope: AA 22-38

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunhistochemie (IHC)

Produktnummer: ABIN180131

Produktbeschreibung

Weitere Bezeichnung: Endothelin-1 Human Big (22-38)

Immunogen: Synthetic peptides of human big endothein-1 (22-38) Purification: Affinity purified with synthetic peptides

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Endothelins are 21 amino acid peptides that are produced ubiquitously by vascular endothelial cells, smooth muscle cells, and other cells in different organs. Endothelins are secreted as big-endothelins that are converted to active proteins by the endothelin-converting enzyme. These peptides possess many biological activities, such as vasoconstriction and mitogenesis, and are involved in numerous physiological and pathophysiological processes in humans. Elevated plasma levels of endothelin have been associated with heart failure, and increased immunoreactivity for endothelin is observed in transplant coronary artery disease.

Spezifität: Endothelin-1 0 % Endothelin-2 0 % Endothelin-3 0 % Big Endothelin-1 100.0 % Big Endothelin-2 <0.1 % Big Endothelin-3 <0.1 % VIC <0.1 %

Anwendungen

Applikationshinweise: This antibody can be stained in formalin fixed paraffin embedded tissues by Immunohistochemical techniques such as SAB Method. The optimal dilution is 3·` 5 ug/ml, however, the dilution rate should be optimized by each laboratories.

Reinigung: Antigen peptide

Buffer: Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1 ml distilled water will be added to the product

Lagerung: Lyophilized product, 5 years at 2 ­ 8 C : Solution, 2 years at ­20 C

Beschränkungen: Nur für Forschungszwecke einsetzbar