Produktbeschreibung » anti-Bcl-1/cyclin D1 Antikörper

Antigen	Bcl-1/cyclin D1
Immunogen	Recombinant Human PRAD1/cyclin D1 (E. coli)
Reaktivität	Human
Wirt	Maus
Klonalität	Monoklonal
Isotyp	IgG »Passende Sekundärantikörper
Beschreibung	Bcl-1/Cyclin D1 belongs to the G1 cyclins and plays a key role in cell cycle regulation during the G1/S transition by cooperating with cyclin-dependent kinases (CDKs). Its overexpression may lead to growth advantage for tumor cells by way of cell cycle progression, and actually it has been reported in various human cancers, e.g., esophageal, breast, and bladder carcinomas. Among hematolymphoid malignancies, cyclin D1 overexpression resulting from translocational activation has also been recognized in a subset of B-chronic lymphocytic leukemia (B-CLL), multiple myeloma, splenic marginal zone lymphoma, hairy cell leukemia, and mantle cell lymphoma.
Klon	5D4
Spezifität	Cross-react with cyclin D2

Anwendungen » anti-Bcl-1/cyclin D1 Antikörper

Applikation	Immunhistochemie (IHC), Western Blot (WB) » Hier finden Sie 3 Protokolle zu den gelisteten Anwendungen
Applikationshinweise	This antibody can be used in formalin fixed paraffin embedded tissues after microwave treatment by several Immunohistochemical techniques. The optimal dilution is 2-5 ug/ml, however, the dilution rate should be optimized by each laboratories. This antibody can be used for western blotting in concentration of 2-5 ug/ml.
Reinigung	Protein A
Buffer	Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1 ml distilled water will be added to the product
Lagerung	Lyophilized product, 5 years at 2 8 : Solution, 2 years at 20
Forschungsgebiet	Krebs
Beschränkungen	Nur für Forschungszwecke einsetzbar

Antigen:	Bcl-1/cyclin D1
Klonalität:	Monoklonal (5D4)
Applikation:	Immunhistochemie (IHC), Western Blot (WB)
Reaktivität:	Human
Wirt:	Maus
Menge:	100 µg
Preis:	324,00 € (Zzgl. Versandkosten und MWSt)
Bestellnummer:	ABIN180071
Verfügbarkeit:	Lieferbar in 10 bis 15 Werktagen