KDR Antikörper

Antigen: KDR

Klonalität: Monoklonal (23B31)

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB), Immunpräzipitation (IP), Durchflusszytometrie (FACS), Neutralisierung (Neut)

Produktnummer: ABIN180066

Produktbeschreibung

Immunogen: Recombinant protein of extracellular domain of human KDR

Isotyp: IgG  (Passende Sekundärantikörper)

Klon: 23B31

Beschreibung: KDR, alternative name Flk-1 (type 2 receptor), is one of the receptors for VEGFs, important growth factors for vasculogenesis, angiogenesis and lymphangiogenesis. Flt-1 (type 1 receptor) is also known as a VEGF receptor. In particular, it is believed that they play important roles in the signal transduction of endothelial and lymphatic endothelial cells. It is understood that after binding with VEGF, Flt-1 and KDR/Flk-1 stimulate the vascular endothelial cells in a coordinated action. This monoclonal antibody recognizes KDR by W.B. and I.P. applications and it enables FACS analysis of KDR-expressing cells. It has been confirmed that the addition of this antibody does not induce ligand-binding-dependent phosphorylation of KDR and it may be used as a neutralizing antibody.

Spezifität: Confirmed by western blotting with HUVEC.

Anwendungen

Applikationshinweise: This antibody can be used for western blotting at 1-5 ug/mL. This antibody can be used for immunoprecipitation at 3-5 ug/mL.

Reinigung: Protein A

Buffer: Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1.0 mL deionized water will be added to the product

Lagerung: Lyophilized product, 5 years at 2 ­ 8 : Solution, 2 years at ­20

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-KDR antibody

anti-KDR antibody (Image 2)

anti-KDR antibody (Image 3)