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ORP150 (Oxygen Regulated Protein, p150) Antikörper
| Antigen | ORP150 (Oxygen Regulated Protein, p150) |
| Klonalität | Monoklonal (2F07) |
| Wirt |
Maus |
| Reaktivität |
Human |
| Applikation |
Immunhistochemie (IHC), Western Blot (WB), Immunpräzipitation (IP)
|
| Produktnummer | ABIN180058 |
| Menge | 100 µg |
| Preis | 324,00 € Zzgl. Versandkosten €40,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 10 bis 15 Werktagen |
Produktbeschreibung
| Immunogen | Recombinant Protein (GST-ORP150 (Leu 508 - Leu 999)) |
| Isotyp | IgG2 (Passende Sekundärantikörper) |
| Klon | 2F07 |
| Beschreibung | Heat shock proteins (HSPs)/stress proteins are molecular chaperones that are induced by various environmental and physiological stimuli. The 150-kDa oxygen-regulated protein (ORP150), a new member of HSP family, functions as a molecular chaperone in the endoplasmic reticulum (1). It is reported that the ORP150 is an integral participant in ischemic cytoprotective pathways. (2). And, the ORP150 is expressed in human wounds along with VEGF. Colocalization of these two molecules was observed in macrophages in the neovasculature, suggesting a role of ORP150 in the promotion of angiogenesis (3). Furthermore, ORP150 is up-regulated in tumors and, in breast tumors, may be associated with tumor invasiveness. |
| Spezifität | Confirmed by using TG and KO mouse |
Anwendungen
| Applikationshinweise | This antibody can be stained in formalin fixed paraffin embedded tissues after microwave pre-treatment *1 by several Immunohistochemical techniques such as Avidin Biotin Complex (ABC) Method. The optimal dilution is about 5 ug/ml, however, the dilution rate should be optimized by each laboratories. *1 Microwave for 1-0 minutes (10mM citric acid buffer pH6.0) : This antibody can be used for western blotting in concentration of about 1 ug /ml. |
| Reinigung | Protein A |
| Buffer | Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1.0 ml distilled water will be added to the product, then the concentration comes to 100 ug/ml |
| Lagerung | Lyophilized product, 5 years at 2 8 : Solution, 2 years at 20 |
| Forschungsgebiet | Krebs |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
