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Endothelin Receptor Type B (EDNRB) (8Z11) Antikörper

Antigen

Endothelin Receptor Type B (EDNRB)

Synonyme ETB, ETBR, ETRB, HSCR, ABCDS, HSCR2, s, ETb, ET-B, ET>B<, ETR-b, Sox10m1, AU022549, Etb, Ednra, MGC142327, EDNRB, etb, etrb, hscr, abcds, hscr2, MGC145633, ednrb, MGC147408
Epitope
Klonalität Monoklonal (8Z11)
Wirt
Reaktivität
Alternativen

Human

Applikation
Alternativen Immunhistochemie (IHC), Western Blot (WB), Immunpräzipitation (IP)
Produktnummer ABIN180056
Menge 100 µg
Preis 324,00 €   Zzgl. Versandkosten €40,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 10 bis 15 Werktagen

Produktbeschreibung

Weitere Bezeichnung ET-BR (Endothelin-B Receptor) (8Z11)
Immunogen ET-1bound recombinant human 6hN-ETBR produced in insect sf-9 cells
Isotyp IgG2a  (Passende Sekundärantikörper)
Klon 8Z11
Beschreibung Two kinds of receptors for Endothelin have been found, namely Endothelin-A (ET-A) receptor and Endothelin-B (ET-B) receptor. ET-A receptor is ET-1 specific and expressed in lung, aorta, atrium, liver, muscle, cerebral cortex, cerebellum, kidney, adrenal, duodenum, colon and placenta at the mRNA or cDNA level, while ET-B receptor lacks isopeptide specificity and is found in liver, lung, placenta, kidney, heart and brain. Cellular localization of ET-receptors in these organs or tissues, however, has not been elucidated, although stromal cells, but not epithelial cells of the breast, express ET-1 receptor in vitro.
Spezifität Confirmed by western blotting

Anwendungen

Applikationshinweise This antibody can be stained in formalin fixed paraffin embedded tissues with micro wave pretreatment (10min, 1-0mM Citrate buffer, pH 5.0) by several Immunohistochemical techniques such as Avidin Biotin Complex (ABC) Method. The optimal dilution is about 5 ug/ml, however, the dilution rate should be optimized by each laboratories. *1 rinsing by running water after formic acid treatment for 5 minutes following de-paraffin. This antibody can be used for western blotting in concentration of 2 - 5 ug /ml.
Reinigung Recombinant human ET-BR
Buffer Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1.0 ml distilled water will be added to the product
Lagerung Lyophilized product, 5 years at 2 ­ 8 : Solution, 2 years at ­20
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Endothelin Receptor Type B (EDNRB)", Typ "Antikörper" finden
Wirte Kaninchen (21), Ziege (1), Maus (1)
Reaktivitäten Human (21), Ratte (Rattus) (7), Maus (5)
Applikationen Western Blot (WB) (20), Immunhistochemie (Paraffinschnitte) (IHC (p)) (9), Immunhistochemie (IHC) (7), Dot Blot (Dot) (2), ELISA (2), Immunfluoreszenz (IF) (2), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (2), Immunpräzipitation (IP) (2), Enzyme Immunoassay (EIA) (1)
Epitope C-Term (5), B27 (1), N-Term (1)