MDMX Antikörper

Antigen: MDMX

Klonalität: Monoklonal (77A1)

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN180048

Produktbeschreibung

Immunogen: Human MDMX Recombinant protein

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: 77A1

Beschreibung: The p53 tumor suppressor protein is stabilized in response to cellular stress, resulting in activation of genes responsible for either cell cycle arrest or apoptosis. The cellular pathway for releasing normal cells from p53- dependent cell cycle arrest involves the MDM2 protein. Recently, a p53- binding protein with homology to MDM2 was identified and called MDMX. Like MDM2, MDMX is able to bind p53 and inhibit p53 transactivation. It is proposed that the MDMX protein may function to maintain a nuclear pool of p53 protein in undamaged cells.

Anwendungen

Applikationshinweise: This antibody can be used for western blotting in concentration of about 1 - 5 ug/ml. Not tested in application for immunohistochemical staining

Reinigung: Protein A

Buffer: Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1.0 ml distilled water will be added to the product

Lagerung: Lyophilized product, 5 years at 2 ­ 8 : Solution, 2 years at ­20

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-MDMX antibody