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Antikörper
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anti-8-Oxoguanine DNA Glycosylase (OGG1) Antikörper
8-Oxoguanine DNA Glycosylase (OGG1) Antikörper
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| Synonyme |
HMMH, MUTM, OGH1, HOGG1, OGG1, ogg1, 8-OXOGUANINE-DNA GLYCOSYLASE 1, F8K7.14, F8K7_14, 19.m02329, Tb04.1H19.930 |
| Klonalität |
Monoklonal (7-00E-02) |
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Wirt
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Reaktivität
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Applikation
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| Produktnummer |
ABIN180046 |
| Menge |
100 µg |
| Preis |
324,00 € Zzgl. Versandkosten €40,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 10 bis 15 Werktagen |
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Weitere Bezeichnung
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OGG1 (8-oxoguanine DNA glycosylase 1)
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Immunogen
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Recombinant Human OGG1
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Isotyp
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IgG1 (Passende Sekundärantikörper)
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Klon
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7-00E-02
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Beschreibung
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Oxidative damage to DNA has been proposed to have a role in cancer and ageing. Oxygen-free radicals formed during normal aerobic cellular metabolism attack bases in DNA, and 7, 8-dihydro-8-oxoguanine (8-oxoG) is one of the adducts formed. Eukaryotic replicative DNA polymerases replicate DNA containing 8-oxoG by inserting an adenine opposite the lesion, consequently, 8-oxoG is highly mutagenic and causes G:C to T:A transversions. Genetic studies in yeast have indicated a role for mismatch repair in minimizing the incidence of these mutations. In Saccharomyces cerevisiae, deletion of OGG1, encoding a DNA glycosylase that functions in the removal of 8-oxoG when
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Applikationshinweise
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This antibody can be used for western blotting in concentration of 1 ug/ml. Reactivity: confirmed in human OGG1 transfectant Reference:Shinmura K., et al. Expression of the OGG1-type 1a(nuclear form) protein in cancerous and non-cancerous human cells. International Journal of Oncology 2-000 1-6: 7-01-707
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Reinigung
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Protein A
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Buffer
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Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1 ml distilled water will be added to the product
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Lagerung
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Lyophilized product, 5 years at 2 8 : Solution, 2 years at 20
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "8-Oxoguanine DNA Glycosylase (OGG1)", Typ "Antikörper" finden
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Wirte
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Kaninchen (23), Ziege (5), Maus (2)
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Reaktivitäten
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Human (22), Ratte (Rattus) (12), Maus (7), Affe (4), Primate (2), Primaten (1)
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Applikationen
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Western Blot (WB) (28), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (9), Immunhistochemie (Paraffinschnitte) (IHC (p)) (9), Enzyme Immunoassay (EIA) (4), ELISA (3), ELISA (Detektionsantikörper) (3), Immunhistochemie (IHC) (2), Dot Blot (Dot) (1), Immunfluoreszenz (IF) (1), Immunpräzipitation (IP) (1)
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Konjugate
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Biotin (1), HRP (1)
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Epitope
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C-Term (3)
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Alternativen 
