anti-S-100 Protein Antikörper

Übersicht

Antigen	S-100 Protein
Immunogen	Bovine Brain S-100 Protein
Reaktivität	Rind (Kuh)
Wirt	Maus
Klonalität	Monoklonal
Isotyp	IgG1 »Passende Sekundärantikörper
Beschreibung	S100 proteins (16 members) show a very divergent pattern of cell- and tissue-specific expression, of subcellular localizations and relocations, of post-translational modifications, and of affinities for Ca2+, Zn2+, and Cu2+, consistent with their pleiotropic intra- and extracellular functions. Up to 40 target proteins are reported to interact with S100 proteins and for S100A1 alone 15 target proteins are presently known. Therefore it is not surprising that many functional roles have been proposed and that several human disorders such as cancer, neurodegenerative diseases, cardiomyopathies, inflammations, diabetes, and allergies are associated with an altered expression of S100 proteins.
Klon	2A10
Spezifität	React to chain of Bovine and Human S-100 protein

Applikation	Immunhistochemie (IHC) » Hier finden Sie 1 verfügbares Protokoll zu den getesteten Anwendungen
Applikationshinweise	This antibody can be stained in formalin fixed paraffin embedded tissues by several Immunohistochemical techniques such as Avidin Biotin Complex (ABC) Method. The optimal dilution is X 2-00, however, the dilution rate should be optimized by each laboratories.
Buffer	Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 0.5 ml distilled water will be added to the product
Lagerung	Lyophilized product, 5 years at 2 8 : Solution, 2 years at 20
Beschränkungen	Nur für Forschungszwecke einsetzbar