S-100 Protein (alpha chain) Antikörper

Antigen: S-100 Protein (alpha chain)

Klonalität: Monoklonal (2A10)

Wirt: Maus

Reaktivität: Rind (Kuh)

Applikation: Immunhistochemie (IHC)

Produktnummer: ABIN180036

Produktbeschreibung

Weitere Bezeichnung: S-100 Protein

Immunogen: Bovine Brain S-100 Protein

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: 2A10

Beschreibung: S100 proteins (16 members) show a very divergent pattern of cell- and tissue-specific expression, of subcellular localizations and relocations, of post-translational modifications, and of affinities for Ca2+, Zn2+, and Cu2+, consistent with their pleiotropic intra- and extracellular functions. Up to 40 target proteins are reported to interact with S100 proteins and for S100A1 alone 15 target proteins are presently known. Therefore it is not surprising that many functional roles have been proposed and that several human disorders such as cancer, neurodegenerative diseases, cardiomyopathies, inflammations, diabetes, and allergies are associated with an altered expression of S100 proteins.

Spezifität: React to chain of Bovine and Human S-100 protein

Anwendungen

Applikationshinweise: This antibody can be stained in formalin fixed paraffin embedded tissues by several Immunohistochemical techniques such as Avidin Biotin Complex (ABC) Method. The optimal dilution is X 2-00, however, the dilution rate should be optimized by each laboratories.

Buffer: Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 0.5 ml distilled water will be added to the product

Lagerung: Lyophilized product, 5 years at 2 ­ 8 : Solution, 2 years at ­20

Beschränkungen: Nur für Forschungszwecke einsetzbar