Vascular Endothelial Growth Factor (VEGF) (16F1) Antikörper

Antigen: Vascular Endothelial Growth Factor (VEGF)

Synonyme: vegf-A, VEGF, DmVEGF-1, EP1624, PVF, PVF1, PVFs, VEGF2-B, Vegf17E, Vegf17e-a, Vegf17e-b, l(1)G0146, vegf1, DmelCG7103, CG7103, DmVEGF-2, PV2, PVF2, VEGF-2, VEGF27Cb, DmelCG13780, CG13780, CG13781, CG13782, CG13783, CG31629, CG4492, DmVEGF-3, PVF3, VEGF27Ca, DmelCG34378, CG34378, vegf, LOC100033839

Epitope: 16F1

Klonalität: Monoklonal (16F1)

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB), Neutralisierung (Neut)

Produktnummer: ABIN180028

Produktbeschreibung

Weitere Bezeichnung: VEGF(16F1)

Immunogen: recombinant Human VEGF (E. coli)

Isotyp: IgG2a  (Passende Sekundärantikörper)

Klon: 16F1

Beschreibung: Vascular Endothelial Cell Growth Factor (VEGF) is a homodimeric protein initially purified from media conditioned by normal bovine pituitary folliculo-stellate cells and secreted by a variety of vascularized tissues. It was subsequently found to be identical to a vascular permeability factor (VPF), which was previously identified in media conditioned by tumor cell lines based upon its ability to increase the permeability of capillary blood vessels. The reported activities of VEGF include stimulation of endothelial cell growth, angiogenesis and capillary permeability. Human VEGF is a 38.2kDa homodimeric protein consisting of two 165 amino acid polypeptide chains. VEGF is expressed in many human tumor cells, including human adenocarcinoma, human pancreatic carcinoma, human hepatocellular carcinoma, renal cell carcinoma, fibrosarcoma, HL60 promyelocytic leukemia, GS-9L glioma and U937 lymphoma cells. In normal tissues, VEGF expression has been observed in activated macrophages, keratinocytes, hepatocytes, smooth muscle cells Leydig cells, embryonic fibroblasts and bronchial and choroids plexus epithelium, renal glomerular visceral epithelium and mesangial cells.

Spezifität: React with Human VEGF (react with only homo dimmer), crossreactivities with rat and mice are not tested.

Synonyme: vegf-A, VEGF, DmVEGF-1, EP1624, PVF, PVF1, PVFs, VEGF2-B, Vegf17E, Vegf17e-a, Vegf17e-b, l(1)G0146, vegf1, DmelCG7103, CG7103, DmVEGF-2, PV2, PVF2, VEGF-2, VEGF27Cb, DmelCG13780, CG13780, CG13781, CG13782, CG13783, CG31629, CG4492, DmVEGF-3, PVF3, VEGF27Ca, DmelCG34378, CG34378, vegf, LOC100033839

Anwendungen

Applikationshinweise: This antibody can be used for western blotting in concentration of 2-5 ug/ml and neutralization assay in concentration at 3 ug/ml (inhibit VEGF activity at 5-0ng/ml)

Reinigung: Protein A

Buffer: Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1 ml distilled water will be added to the product

Lagerung: Lyophilized product, 5 years at 2 ­ 8 : Solution, 2 years at ­20

Beschränkungen: Nur für Forschungszwecke einsetzbar