Lymphocyte Antigen 9 (LY9) Antikörper (PE)

Antigen: Lymphocyte Antigen 9 (LY9)

Synonyme: hly9, mLY9, CD229, SLAMF3, LY9, MGC139478, Ly-9, T100, Lgp100, AI893573

Klonalität: Monoklonal (HLy-9-1-25)

Wirt: Maus

Reaktivität: Human

Konjugat: PE

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN179954

Produktbeschreibung

Weitere Bezeichnung: CD229 (Ly-9)

Immunogen: 300.19 cell line transfected with the CD229 full-length DNA

Isotyp: IgG1, kappa chain

Klon: HLy-9-1-25

Beschreibung: CD229 is a 100-120 kD glycoprotein. It is a member of the SLAM family, a CD2 subset of the Ig superfamily, known as Ly9 or SLAMF3. CD229 is expressed on T cells, B cells, NK cells, and thymocytes. It functions as a homophilic adhesion molecule through binding to CD229 itself. The cytoplasmic tail of CD229 binds to SAP and Grb2 proteins. CD229 is involved in enhancing T cell activation and Th2 polarization. HLy9.1.25 antibody recognizes epitope A in the first Ig domain of Ly9 molecule. Distribution: T cells, B cells, NK cells, thymocytes Function: Homophilic adhesion, T cell activation, Th2 cell polarization Synonyms: Ly9, Ly-9, SLAMF3 Structure: 100-120 kD glycoprotein, SLAM family, CD2 subset of Ig superfamily

Anwendungen

Applikationshinweise: Additional reported (for the relevant formats) applications include: immunoprecipitation, and immunocytochemistry.The LEAF(TM) purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm sterile-filtered) is recommended for functional assays (ABIN179950). Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 µl per million cells or 20 µl per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Reinigung: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Lagerung: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Forschungsgebiet: CD Antigene

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Lymphocyte Antigen 9 (LY9) antibody (PE)