Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) Antikörper (APC/Cy7)

Antigen: Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C)

Synonyme: BAFFR, CD268, BAFF-R, MGC138235, RGD1560810, TNFRSF13C

Klonalität: Monoklonal (11C1)

Wirt: Maus

Reaktivität: Human

Konjugat: APC,Cy7

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN179895

Produktbeschreibung

Weitere Bezeichnung: CD268 (BAFF-R| BAFFR)

Immunogen: BAFF-R-L1.2 transfectants

Isotyp: IgG1, kappa chain

Klon: 11C1

Beschreibung: B cell-activating factor receptor (BAFF-R) is a 19 kD type III membrane protein. It belongs to TNFR superfamily, also known as TNFRSF member 13C (TNFRSF13C), BAFF receptor 3 (BR3), or CD268. BAFF-R is expressed on mature B cells, B cell lymphoma, and T cell subset. BAFF-R is the major receptor for BAFF/BLys (or TALL-1, THANK) which binds to TACI and BCMA as well. The interaction of BAFF with BAFF-R promotes NF-kappa B activation and plays predominant roles in B-cell maturation and survival as well as costimulates T cell activation and proliferation. TRAF3 is a BAFF-R intracellularly associated protein, which negatively regulates BAFF-R-mediated NF-kappa B activation. Distribution: Mature B cells, B cell lymphoma, T cell subset Function: Induce B cell proliferation and immunoglobulin secretion, costimulate T cell activation Synonyms: TNFRSF13C, BAFF-R, BAFFR, BR3, BAFF Receptor Structure: Type III transmembrane protein, TNF receptor superfamily, 19 kD

Anwendungen

Applikationshinweise: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 µl per million cells or 20 µl per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Reinigung: The antibody was purified by affinity chromatography, and conjugated with APC/Cy7 under optimal conditions. The solution is free of unconjugated APC/Cy7 and unconjugated antibody.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Lagerung: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Forschungsgebiet: CD Antigene

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) antibody (APC/Cy7)