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CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antikörper (FITC)

Antigen

CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40)
Synonyme p50, Bp50, CDW40, MGC9013, TNFRSF5, IGM, GP39, IMD3, TRAP, HIGM1, T-BAM, Tnfrsf5, AI326936, CD40
Klonalität Monoklonal (G28-5)
Wirt
Reaktivität
Alternativen

Human
Konjugat
Applikation
Alternativen Durchflusszytometrie (FACS)
Produktnummer ABIN179865
Menge 100 tests  (Varianten)
Preis Produkt für diese Region nicht verfügbar.
Lieferung nach

anti-CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) antibody (FITC)

Produktbeschreibung
Anwendungen Bilder Alternativen Varianten zurück nach oben

Weitere Bezeichnung CD40
Isotyp IgG1, kappa chain
Klon G28-5
Beschreibung CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The G28.5 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA. Distribution: B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts Function: B cell differentiation, costimulation, isotype class-switching, rescues B cells from apoptosis Synonyms: BP50, TNFRSF5 Structure: TNFR superfamily, type I glycoprotein, 48 kD

Anwendungen
Bilder Alternativen Varianten zurück nach oben

Applikationshinweise Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Additional reported applications (for the relevant formats) include: B cell bioassays. For immunofluorescent staining, the suggested use of this reagent is 20 µl per 1 million cells or 20 µl per 100 µl of whole blood.
Reinigung The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Lagerung The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Forschungsgebiet CD Antigene
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen
Anwendungen Bilder Varianten zurück nach oben

Alternativen zu Antigen "CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40)", Typ "Antikörper" finden
Wirte Maus (178), Ratte (110), Hamster (38), Kaninchen (28), Ziege (1)
Reaktivitäten Human (198), Maus (160), Ratte (Rattus) (11), Affe (7), Huhn (5), Hund (4), Schwein (4), Rind (Kuh) (1), Hamster (1), Nerz (1), Kaninchen (1), Schaf (1)
Applikationen Durchflusszytometrie (FACS) (293), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (49), Immunpräzipitation (IP) (45), Western Blot (WB) (43), Funktionale Studien (Func) (34), ELISA (28), Immunhistochemie (IHC) (28), Immunhistochemie (Paraffinschnitte) (IHC (p)) (25), Enzyme Immunoassay (EIA) (14), Immunfluoreszenz (IF) (10), Blockierende Antikörper (Inhibition) (6), Kostimulation (6), Immunzytochemie (ICC) (2), Blocking Antibody (Inhibition) (1), Dot Blot (Dot) (1), ELISA (Detektionsantikörper) (1), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (1)
Konjugate FITC (52), Biotin (44), PE (42), APC (18), Alexa Fluor 647 (8), RPE (5), Alexa Fluor 488 (3), SPRD (3), Cy5,PE (2), Cy5.5,PE (2), PE,Cy5 (2), PerCP,Cy5.5 (2)
Epitope pThr254 (1)