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CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antikörper
| Antigen | CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) |
| Synonyme | p50, Bp50, CDW40, MGC9013, TNFRSF5, IGM, GP39, IMD3, TRAP, HIGM1, T-BAM, Tnfrsf5, AI326936, CD40 |
| Klonalität | Monoklonal (G28-5) |
| Wirt |
Alternativen Maus |
| Reaktivität |
Alternativen Human |
| Applikation |
Alternativen Durchflusszytometrie (FACS)
|
| Produktnummer | ABIN179863 |
| Menge | 100 µg (Varianten) |
| Preis | Produkt für diese Region nicht verfügbar. |
| Lieferung nach |
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Produktbeschreibung
| Weitere Bezeichnung | CD40 |
| Format | Purified |
| Isotyp | IgG1, kappa chain (Passende Sekundärantikörper) |
| Klon | G28-5 |
| Beschreibung | CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The G28.5 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA. Distribution: B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts Function: B cell differentiation, costimulation, isotype class-switching, rescues B cells from apoptosis Synonyms: BP50, TNFRSF5 Structure: TNFR superfamily, type I glycoprotein, 48 kD |
Anwendungen
| Applikationshinweise | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Additional reported applications (for the relevant formats) include: B cell bioassays. For immunofluorescent staining, the suggested use of this reagent is < 0.5 µg per 10 cells in 100 µl volume. |
| Reinigung | The antibody was purified by affinity chromatography. |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Lagerung | The antibody solution should be stored undiluted at 4°C. |
| Forschungsgebiet | CD Antigene |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
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