Apolioprotein A5 (APOA5) Antikörper

Antigen: Apolioprotein A5 (APOA5)

Synonyme: RAP3, Apoav, 1300007O05Rik, APOAV, APOA-V, MGC126836, MGC126838, MGC108612, APOA5, MGC140487

Klonalität: Monoklonal (2G1H11)

Wirt: Maus

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN173293

Produktbeschreibung

Immunogen: Source of Antigen: E. coli

Format: Protein G purified

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: 2G1H11

Beschreibung: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model human ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. In, additions, peroxisome proliferators-activated receptor-agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Despite these compelling molecular biology data, relatively little is known about ApoA5 protein in human serum. Recently, it was demonstrated that ApoA5 is the present in the human serum detected by polyclonal antibodies against both the HN2 and COOH termini, although at much lower concentration than other apolipoproteins

Anwendungen

Applikationshinweise: ELISA: 1:4000. WB: 1:1000 to 1:2000

Konzentration: 1 mg/ml

Reinigung: Affinity chromatography on a column with immobilized protein G.

Buffer: Concentration of antibody is 1 mg/ml in 50% Glycerol in PBS, pH 7.2. AZIDE FREE.

Lagerung: The antibody remains stable and fully active until the expiry date when stored at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated and freezing thawing. Aliquot with Sodium Azide will be stable at 4ºC for 3 months.

Beschränkungen: Nur für Forschungszwecke einsetzbar