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NRF2 Antikörper (AA 356-589)

Name: NRF2 Antikörper (AA 356-589)
Brand: antibodies-online
SKU: ABIN1724931
Price: 614.71 EUR
Availability: InStock

NFE2L2 Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 1A6G6 unconjugated

Western blot analysis using NFE2L2 mAb against human NFE2L2 (AA: 356-589) recombinant protein.

Western blot analysis using NFE2L2 mAb against HEK293 (1) and NFE2L2 (AA: 356-589)-hIgGFc transfected HEK293 (2) cell lysate.

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng),

ELISA

Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using NFE2L2 mouse mAb with DAB staining.

IHC

4 Abbildungen

(1 reference)

Produktnummer ABIN1724931

Datenblatt (PDF)

Target Alle NRF2 (NFE2L2) Antikörper anzeigen

NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
Bindungsspezifität
22

15

9

8

8

7

7

4

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 356-589
Reaktivität
113

57

55

5

4

3

2

2

1

1

1

1

1

1
Human
Wirt
107

8

1
Maus
Passende Sekundärantikörper
Klonalität
98

18
Monoklonal
Konjugat
57

10

6

6

4

4

4

4

4

4

4

3

1

1

1

1

1

1
Dieser NRF2 Antikörper ist unkonjugiert
Applikation
89

51

23

23

18

15

15

14

14

10

7

2

2

2

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung

purified

Immunogen

Purified recombinant fragment of human NFE2L2 (AA: 356-589) expressed in E. coli.

Klon

1A6G6

Isotyp

IgG1

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Applikationshinweise

ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

4°C, -20°C for long term storage
Sandford, Malhotra, Boezen, Siedlinski, Postma, Wong, Akhabir, He, Connett, Anthonisen, Paré, Biswal: "NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease." in: Physiological genomics, Vol. 44, Issue 15, pp. 754-63, (2012) (PubMed).
Target

NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Andere Bezeichnung

NFE2L2 (NFE2L2 Produkte)

Synonyme

Nrf2 antikoerper, nfe2l2 antikoerper, wu:fc15g09 antikoerper, wu:fj67e03 antikoerper, NF-E2R2 antikoerper, NRF2 antikoerper, AI194320 antikoerper, nuclear factor, erythroid 2-like 2a antikoerper, nuclear factor, erythroid 2 like 2 S homeolog antikoerper, nuclear factor, erythroid 2 like 2 antikoerper, nuclear factor, erythroid derived 2, like 2 antikoerper, nuclear factor, erythroid 2-like 2 antikoerper, nfe2l2a antikoerper, nfe2l2.S antikoerper, NFE2L2 antikoerper, Nfe2l2 antikoerper

Hintergrund

Description: This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters, many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene. ,
Aliases: NRF2

Molekulargewicht

67.8 kDa

Gen-ID

4780

HGNC

4780

Pathways

ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling