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MME Antikörper (AA 52-246)

Name: MME Antikörper (AA 52-246)
Brand: antibodies-online
SKU: ABIN1724914
Price: 614.71 EUR
Availability: InStock

MME Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal 7D4B1 unconjugated

Western blot analysis using CD10 mouse mAb against LNCAP cell lysate.

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng),

ELISA

Western blot analysis using CD10 mAb against human CD10 (AA: 52-246) recombinant protein.

Western blot analysis using CD10 mAb against HEK293 (1) and CD10 (AA: 52-246)-hIgGFc transfected HEK293 (2) cell lysate.

Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using CD10 mouse mAb with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CD10 mouse mAb with DAB staining.

IHC

6 Abbildungen

(1 reference)

Produktnummer ABIN1724914

Datenblatt (PDF)

Target Alle MME Antikörper anzeigen

MME (Membrane Metallo-Endopeptidase (MME))
Bindungsspezifität
16

14

10

8

8

7

7

7

7

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 52-246
Reaktivität
212

58

50

3

2

2

2

2

2

1

1

1

1
Human
Wirt
110

108

2
Maus
Passende Sekundärantikörper
Klonalität
114

105

2
Monoklonal
Konjugat
107

19

19

14

9

6

5

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser MME Antikörper ist unkonjugiert
Applikation
131

101

79

68

38

29

22

21

13

13

10

8

6

5

5

3

2

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung

purified

Immunogen

Purified recombinant fragment of human CD10 (AA: 52-246) expressed in E. coli.

Klon

7D4B1

Isotyp

IgG1
anti-Membrane Metallo-Endopeptidase (MME) (AA 52-352) antibody
MME Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 382-538) antibody
MME Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 501-600) antibody
MME Reaktivität: Human, Maus, Ratte FACS, WB, ELISA, IHC (p), ICC, IHC (fro), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME Reaktivität: Human WB, IHC, StM Wirt: Maus Monoclonal MME-1870 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 286-428) antibody
MME Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) antibody (FITC)
MME Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-78 FITC

anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibody
MME Reaktivität: Human FACS, WB, IHC, ELISA, ICC, Neut Wirt: Maus Monoclonal 6G12E12 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME Reaktivität: Human WB, IHC, ELISA, StM, Coat Wirt: Maus Monoclonal MME-1892 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody
MME Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) antibody
MME Reaktivität: Human FACS, IP Wirt: Maus Monoclonal MEM-78 unconjugated

Applikationshinweise

ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

4°C, -20°C for long term storage
Thomas-Pfaab, Annereau, Munsch, Guilbaud, Garrido, Paul, Brousset, Lamant, Meyer: "CD10 expression by melanoma cells is associated with aggressive behavior in vitro and predicts rapid metastatic progression in humans." in: Journal of dermatological science, Vol. 69, Issue 2, pp. 105-13, (2013) (PubMed).
Target

MME (Membrane Metallo-Endopeptidase (MME))

Andere Bezeichnung

CD10 (MME Produkte)

Synonyme

CALLA antikoerper, CD10 antikoerper, NEP antikoerper, SFE antikoerper, 6030454K05Rik antikoerper, C85356 antikoerper, Nep antikoerper, neprilysin antikoerper, membrane metalloendopeptidase antikoerper, membrane metallo endopeptidase antikoerper, membrane metallo-endopeptidase antikoerper, MME antikoerper, Mme antikoerper

Substanzklasse

Chemical

Hintergrund

Description: This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. ,
Aliases: MME, NEP, SFE, CALLA

Molekulargewicht

85.5 kDa

Gen-ID

4311

HGNC

4311

Pathways

RTK Signalweg, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration