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IGFBP7 Antikörper (AA 52-156)

IGFBP7 Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 1D9E7 unconjugated
Produktnummer ABIN1724903
  • Target Alle IGFBP7 Antikörper anzeigen
    IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
    Bindungsspezifität
    • 15
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 52-156
    Reaktivität
    • 48
    • 23
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 47
    • 3
    • 2
    • 1
    Maus
    Klonalität
    • 46
    • 6
    • 1
    Monoklonal
    Konjugat
    • 27
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IGFBP7 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 19
    • 13
    • 13
    • 12
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human IGFBP7 (AA: 52-156) expressed in E. coli.
    Klon
    1D9E7
    Isotyp
    IgG1
    Top Product
    Discover our top product IGFBP7 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Evdokimova, Tognon, Benatar, Yang, Krutikov, Pollak, Sorensen, Seth: "IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors." in: Science signaling, Vol. 5, Issue 255, pp. ra92, (2012) (PubMed).

  • Target
    IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
    Andere Bezeichnung
    IGFBP7 (IGFBP7 Produkte)
    Synonyme
    zgc:85888 antikoerper, AGM antikoerper, FSTL2 antikoerper, IBP-7 antikoerper, IGFBP-7 antikoerper, IGFBP-7v antikoerper, IGFBPRP1 antikoerper, MAC25 antikoerper, PSF antikoerper, RAMSVPS antikoerper, TAF antikoerper, Fstl2 antikoerper, Mac25 antikoerper, insulin like growth factor binding protein 7 antikoerper, insulin-like growth factor binding protein 7 antikoerper, IGFBP7 antikoerper, igfbp7 antikoerper, Igfbp7 antikoerper
    Hintergrund

    Description: This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). ,

    Aliases: AGM, PSF, TAF, FSTL2, IBP-7, MAC25, IGFBP-7, RAMSVPS, IGFBP-7v, IGFBPRP1

    Molekulargewicht
    29.1 kDa
    Gen-ID
    3490
    HGNC
    3490
    Pathways
    Growth Factor Binding
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