ABCG5 Antikörper (AA 306-367)

Produktnummer ABIN1724857

Produktdetails anti-ABCG5 Antikörper

Target: ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))

Bindungsspezifität: AA 306-367

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ABCG5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human ABCG5 (AA: 306-367) expressed in E. coli.

Klon: 1B5E10

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-ABCG5 Antikörper (ABIN1724857)

Li, Yin, Wei, Yan, Aung, Wu, Wu, Lin, Liu, Pan: "ATP-binding cassette transporter G5 and G8 polymorphisms and several environmental factors with serum lipid levels." in: PLoS ONE, Vol. 7, Issue 5, pp. e37972, (2012) (PubMed).

Johnson, Lee, Pickert, Urbatsch: "Bile acids stimulate ATP hydrolysis in the purified cholesterol transporter ABCG5/G8." in: Biochemistry, Vol. 49, Issue 16, pp. 3403-11, (2010) (PubMed).

Details zu ABCG5

Target: ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))

Andere Bezeichnung: ABCG5 (ABCG5 Produkte)

Synonyme: DDBDRAFT_0205617 antikoerper, DDBDRAFT_0215344 antikoerper, DDB_0205617 antikoerper, DDB_0215344 antikoerper, STSL antikoerper, AW112016 antikoerper, cmp antikoerper, sterolin-1 antikoerper, trac antikoerper, ATP binding cassette subfamily G member 5 antikoerper, ATP-binding cassette, sub-family G (WHITE), member 5 antikoerper, ABC transporter G family protein antikoerper, ABCG5 antikoerper, abcg5 antikoerper, abcG5 antikoerper, Abcg5 antikoerper

Hintergrund:

Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. , ,

Aliases: STSL

Molekulargewicht: 72.5 kDa

Gen-ID: 64240

HGNC: 64240

Pathways: Lipid Metabolism