ABCG5 Antikörper (AA 306-367)
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- Target Alle ABCG5 Antikörper anzeigen
- ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))
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Bindungsspezifität
- AA 306-367
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ABCG5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human ABCG5 (AA: 306-367) expressed in E. coli.
- Klon
- 1B5E10
- Isotyp
- IgG1
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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ATP-binding cassette transporter G5 and G8 polymorphisms and several environmental factors with serum lipid levels." in: PLoS ONE, Vol. 7, Issue 5, pp. e37972, (2012) (PubMed).
: "Bile acids stimulate ATP hydrolysis in the purified cholesterol transporter ABCG5/G8." in: Biochemistry, Vol. 49, Issue 16, pp. 3403-11, (2010) (PubMed).
: "
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ATP-binding cassette transporter G5 and G8 polymorphisms and several environmental factors with serum lipid levels." in: PLoS ONE, Vol. 7, Issue 5, pp. e37972, (2012) (PubMed).
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- Target
- ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))
- Andere Bezeichnung
- ABCG5 (ABCG5 Produkte)
- Synonyme
- DDBDRAFT_0205617 antikoerper, DDBDRAFT_0215344 antikoerper, DDB_0205617 antikoerper, DDB_0215344 antikoerper, STSL antikoerper, AW112016 antikoerper, cmp antikoerper, sterolin-1 antikoerper, trac antikoerper, ATP binding cassette subfamily G member 5 antikoerper, ATP-binding cassette, sub-family G (WHITE), member 5 antikoerper, ABC transporter G family protein antikoerper, ABCG5 antikoerper, abcg5 antikoerper, abcG5 antikoerper, Abcg5 antikoerper
- Hintergrund
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Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. , ,
Aliases: STSL
- Molekulargewicht
- 72.5 kDa
- Gen-ID
- 64240
- HGNC
- 64240
- Pathways
- Lipid Metabolism
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