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FLIP Antikörper (AA 100-251)

CFLAR Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 6G11A6 unconjugated
Produktnummer ABIN1724856
  • Target Alle FLIP (CFLAR) Antikörper anzeigen
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    Bindungsspezifität
    • 16
    • 15
    • 15
    • 10
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-251
    Reaktivität
    • 96
    • 67
    • 57
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 86
    • 15
    • 2
    Maus
    Klonalität
    • 88
    • 15
    Monoklonal
    Konjugat
    • 55
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Dieser FLIP Antikörper ist unkonjugiert
    Applikation
    • 98
    • 39
    • 27
    • 26
    • 21
    • 20
    • 14
    • 14
    • 13
    • 10
    • 8
    • 5
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human CFLAR (AA: 100-251) expressed in E. coli.
    Klon
    6G11A6
    Isotyp
    IgG1
    Top Product
    Discover our top product CFLAR Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Rao-Bindal, Rao, Yu, Kleinerman: "Expression of c-FLIP in pulmonary metastases in osteosarcoma patients and human xenografts." in: Pediatric blood & cancer, Vol. 60, Issue 4, pp. 575-9, (2013) (PubMed).

    Noh, Lee, Sung, Song, Kim, Woo, Kwon, Lee: "CHOP down-regulates cFLIP(L) expression by promoting ubiquitin/proteasome-mediated cFLIP(L) degradation." in: Journal of cellular biochemistry, Vol. 113, Issue 12, pp. 3692-700, (2012) (PubMed).

  • Target
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    Andere Bezeichnung
    CFLAR (CFLAR Produkte)
    Synonyme
    Clarp1 antikoerper, cflar antikoerper, CFLAR antikoerper, FLIP antikoerper, CASH antikoerper, CASP8AP1 antikoerper, CLARP antikoerper, Casper antikoerper, FLAME antikoerper, FLAME-1 antikoerper, FLAME1 antikoerper, I-FLICE antikoerper, MRIT antikoerper, c-FLIP antikoerper, c-FLIPL antikoerper, c-FLIPR antikoerper, c-FLIPS antikoerper, 2310024N18Rik antikoerper, A430105C05Rik antikoerper, Cash antikoerper, ENSMUSG00000072980 antikoerper, Flip antikoerper, Gm9845 antikoerper, c-Flip antikoerper, CASP8 and FADD-like apoptosis regulator a antikoerper, CASP8 and FADD like apoptosis regulator antikoerper, CASP8 and FADD like apoptosis regulator S homeolog antikoerper, CASP8 and FADD-like apoptosis regulator antikoerper, cflara antikoerper, CFLAR antikoerper, cflar antikoerper, cflar.S antikoerper, Cflar antikoerper
    Hintergrund

    Description: The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. , ,

    Aliases: CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1

    Molekulargewicht
    55.3 kDa
    Gen-ID
    8837
    HGNC
    8837
    Pathways
    Apoptose, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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