Paired Box 3 Antikörper (AA 142-203)

Produktnummer ABIN1724816

Produktdetails anti-Paired Box 3 Antikörper

Target: Paired Box 3 (PAX3)

Bindungsspezifität: AA 142-203

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Paired Box 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human PAX3 (AA: 142-203) expressed in E. coli.

Klon: 7D8G7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-Paired Box 3 Antikörper (ABIN1724816)

Dong, Li, Cao, Liu, Pier, Chen, Xu, Chen, Wang, Cui: "FGF2 regulates melanocytes viability through the STAT3-transactivated PAX3 transcription." in: Cell death and differentiation, Vol. 19, Issue 4, pp. 616-22, (2012) (PubMed).

Details zu Paired Box 3

Target: Paired Box 3 (PAX3)

Andere Bezeichnung: PAX3 (PAX3 Produkte)

Synonyme: PAX3 antikoerper, cdhs antikoerper, hup2 antikoerper, pax-3 antikoerper, ws1 antikoerper, xpax3 antikoerper, Pax3 antikoerper, pax3 antikoerper, pax3b antikoerper, xPax3-B antikoerper, CDHS antikoerper, HUP2 antikoerper, WS1 antikoerper, WS3 antikoerper, Pax-3 antikoerper, Sp antikoerper, splotch antikoerper, zgc:92547 antikoerper, paired box 3 antikoerper, paired box 3 L homeolog antikoerper, paired box 3a antikoerper, PAX3 antikoerper, pax3 antikoerper, pax3.L antikoerper, Pax3 antikoerper, pax3a antikoerper

Hintergrund:

Description: This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. , ,

Aliases: WS1, WS3, CDHS, HUP2

Molekulargewicht: 53 kDa

Gen-ID: 5077

HGNC: 5077

Pathways: Sensory Perception of Sound, Tube Formation