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RUNX3 Antikörper (AA 186-252)

RUNX3 Reaktivität: Human, Maus WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 2B3 unconjugated
Produktnummer ABIN1724742
  • Target Alle RUNX3 Antikörper anzeigen
    RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
    Bindungsspezifität
    • 16
    • 16
    • 10
    • 9
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 186-252
    Reaktivität
    • 105
    • 42
    • 32
    • 15
    • 14
    • 13
    • 2
    • 2
    • 1
    Human, Maus
    Wirt
    • 94
    • 14
    • 1
    Maus
    Klonalität
    • 98
    • 11
    Monoklonal
    Konjugat
    • 41
    • 9
    • 9
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser RUNX3 Antikörper ist unkonjugiert
    Applikation
    • 96
    • 39
    • 37
    • 27
    • 26
    • 23
    • 15
    • 10
    • 9
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. coli.
    Klon
    2B3
    Isotyp
    IgG2b
    Top Product
    Discover our top product RUNX3 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Mei, Bai, Liu, Li, Wu, Yu, Zheng: "RUNX3 expression is lost in glioma and its restoration causes drastic suppression of tumor invasion and migration." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 12, pp. 1823-30, (2011) (PubMed).

  • Target
    RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
    Andere Bezeichnung
    RUNX3 (RUNX3 Produkte)
    Synonyme
    runxb antikoerper, RUNX3 antikoerper, CBFA3 antikoerper, frrunx3 antikoerper, runx3 antikoerper, aml2 antikoerper, cbfa3 antikoerper, pebp2ac antikoerper, AML2 antikoerper, Cbfa3 antikoerper, Pebp2a3 antikoerper, PEBP2aC antikoerper, runt-related transcription factor 3 antikoerper, runt related transcription factor 3 antikoerper, runt related transcription factor 3 L homeolog antikoerper, runx3 antikoerper, RUNX3 antikoerper, runx3.L antikoerper, Runx3 antikoerper
    Hintergrund

    Description: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

    Aliases: AML2, CBFA3, PEBP2aC, FLJ34510, MGC16070

    Molekulargewicht
    44.4 kDa
    Gen-ID
    864
    HGNC
    864
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