ZBTB7B Antikörper

Produktnummer ABIN1724728

Produktdetails anti-ZBTB7B Antikörper

Target: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ZBTB7B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human ZBTB7B expressed in E. coli.

Klon: 7C12

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-ZBTB7B Antikörper (ABIN1724728)

Egawa: "Runx and ThPOK: a balancing act to regulate thymocyte lineage commitment." in: Journal of cellular biochemistry, Vol. 107, Issue 6, pp. 1037-45, (2009) (PubMed).

Ghayor, Herrouin, Chadjichristos, Ala-Kokko, Takigawa, Pujol, Galéra: "Regulation of human COL2A1 gene expression in chondrocytes. Identification of C-Krox-responsive elements and modulation by phenotype alteration." in: The Journal of biological chemistry, Vol. 275, Issue 35, pp. 27421-38, (2000) (PubMed).

Details zu ZBTB7B

Target: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Andere Bezeichnung: ZBTB7B (ZBTB7B Produkte)

Synonyme: THPOK antikoerper, ZBTB15 antikoerper, ZFP-67 antikoerper, ZFP67 antikoerper, ZNF857B antikoerper, c-KROX antikoerper, hcKROX antikoerper, Thpok antikoerper, Zfp67 antikoerper, c-Krox antikoerper, ZBTB7B antikoerper, zbtb7b antikoerper, MGC130914 antikoerper, zinc finger and BTB domain containing 7B antikoerper, kruppel-related zinc finger protein hcKrox antikoerper, ZBTB7B antikoerper, Zbtb7b antikoerper, zbtb7b antikoerper

Hintergrund:

Description: ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.

Aliases: THPOK, ZFP67, ZBTB15, c-Krox, hcKrox, ZNF857B, DKFZp686G01254, ZBTB7B

Molekulargewicht: 58 kDa

Gen-ID: 51043

HGNC: 51043