CD20 Antikörper

Produktnummer ABIN1724682

Produktdetails anti-CD20 Antikörper

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD20 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Sequenz: EPANPSEKNS PSTQY

Immunogen: Synthetic peptide corresponding to aa (EPANPSEKNSPSTQY) of human CD20,conjugated to KLH.

Klon: 3E9D3C1G3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-CD20 Antikörper (ABIN1724682)

Byar: "Educating patients about radioimmunotherapy with yttrium 90 ibritumomab tiuxetan (Zevalin)." in: Seminars in oncology nursing, Vol. 20, Issue 1 Suppl 1, pp. 20-5, (2004) (PubMed).

Reiners, Hansen, Krüssmann, Schön, Csernok, Gross, Engert, Von Strandmann: "Selective killing of B-cell hybridomas targeting proteinase 3, Wegener's autoantigen." in: Immunology, Vol. 112, Issue 2, pp. 228-36, (2004) (PubMed).

Details zu CD20

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Andere Bezeichnung: CD20 (MS4A1 Produkte)

Synonyme: B1 antikoerper, Bp35 antikoerper, CD20 antikoerper, CVID5 antikoerper, LEU-16 antikoerper, MS4A2 antikoerper, S7 antikoerper, AA960661 antikoerper, Cd20 antikoerper, Ly-44 antikoerper, Ms4a2 antikoerper, MS4A1 antikoerper, bp35 antikoerper, cd20 antikoerper, ms4a2 antikoerper, leu-16 antikoerper, ms4a4c antikoerper, cd20-like antikoerper, membrane spanning 4-domains A1 antikoerper, membrane-spanning 4-domains, subfamily A, member 1 antikoerper, B-lymphocyte antigen CD20 antikoerper, MS4A1 antikoerper, Ms4a1 antikoerper, ms4a1 antikoerper, LOC101694281 antikoerper

Hintergrund:

Description: CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 Molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1.

Aliases: B1, S7, Bp35, CD20, MS4A2, LEU-16, MGC3969, MS4A1

Gen-ID: 931

HGNC: 931