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CD81 Antikörper

CD81 Reaktivität: Human FACS, cELISA Wirt: Ratte Monoclonal QV-6A8-S3 unconjugated
Produktnummer ABIN1720914
  • Target Alle CD81 Antikörper anzeigen
    CD81
    Reaktivität
    • 118
    • 102
    • 40
    • 18
    • 17
    • 7
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 65
    • 60
    • 32
    • 14
    • 2
    • 1
    Ratte
    Klonalität
    • 123
    • 45
    • 3
    Monoklonal
    Konjugat
    • 73
    • 20
    • 17
    • 16
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD81 Antikörper ist unkonjugiert
    Applikation
    • 125
    • 79
    • 44
    • 41
    • 31
    • 29
    • 29
    • 27
    • 17
    • 15
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Cell-ELISA (cELISA)
    Spezifität
    Anti-human CD81 (TAPA-1)
    Produktmerkmale
    Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
    Aufreinigung
    Protein G
    Immunogen
    genetic immunisation with cDNA encoding human CD81
    Klon
    QV-6A8-S3
    Isotyp
    IgG2b
    Top Product
    Discover our top product CD81 Primärantikörper
  • Applikationshinweise
    Flow cytometry: 1.2 µg/10^6 cells
    ELISA: 1:200 - 1:400
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    Kommentare

    Synonyms: TAPA-1

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, pH 7.2
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C
    Informationen zur Lagerung
    short term: 2 °C - 8 °C, long term: -20 °C
  • Fofana, Xiao, Thumann, Turek, Zona, Tawar, Grunert, Thompson, Zeisel, Baumert: "A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission." in: PLoS ONE, Vol. 8, Issue 5, pp. e64221, (2013) (PubMed).

  • Target
    CD81
    Andere Bezeichnung
    CD81 (CD81 Produkte)
    Synonyme
    Tapa-1 antikoerper, Tapa1 antikoerper, Tspan28 antikoerper, CVID6 antikoerper, S5.7 antikoerper, TAPA1 antikoerper, TSPAN28 antikoerper, CD81 molecule antikoerper, CD81 molecule b antikoerper, CD81 antigen antikoerper, Cd81 molecule antikoerper, CD81 antikoerper, cd81b antikoerper, Cd81 antikoerper
    Hintergrund
    CD81 (TAPA-1) belongs to the transmembrane 4 superfamily (tetraspanin family). CD81 is a widely expressed cell-surface protein that is characterized by the presence of four transmembranic domains, short N and C termini, a small extracellular loop (SEL) and a large extra-cellular loop (LEL). It is expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin and plays a role in the regulation of cell development, cell-growth and signal transduction. CD81 plays a critical role in Hepatitis C Infection and is involved in HCV entry due to its ability to interact with virus' E1/E2 glycoproteins. CD81 is an essential HCV host factor as silencing of CD81 expression by CD81-specific monoclonal antibodies in hepatoma cells inhibits HCV entry.
    UniProt
    P60033
    Pathways
    Inositol Metabolic Process, Hepatitis C
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