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LGR4 Antikörper

LGR4 Reaktivität: Human FACS, cELISA Wirt: Ratte Monoclonal BBX-1H1 unconjugated
Produktnummer ABIN1720913
  • Target Alle LGR4 Antikörper anzeigen
    LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))
    Reaktivität
    • 34
    • 13
    • 11
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 27
    • 4
    • 3
    Ratte
    Klonalität
    • 27
    • 7
    Monoklonal
    Konjugat
    • 23
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LGR4 Antikörper ist unkonjugiert
    Applikation
    • 12
    • 10
    • 8
    • 7
    • 4
    • 4
    • 2
    • 1
    Flow Cytometry (FACS), Cell-ELISA (cELISA)
    Spezifität
    Anti-human LGR4
    Keine Kreuzreaktivität
    Maus
    Produktmerkmale
    Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
    Aufreinigung
    Protein G
    Immunogen
    genetic immunisation with cDNA encoding human LGR4
    Klon
    BBX-1H1
    Isotyp
    IgG2a kappa
  • Applikationshinweise
    Flow cytometry: 1.2 µg/10^6 cells
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    Kommentare

    Synonyms: GPR48

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, pH 7.2
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C
    Informationen zur Lagerung
    short term: 2 °C - 8 °C, long term: -20 °C
  • Target
    LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))
    Andere Bezeichnung
    LGR4 (LGR4 Produkte)
    Synonyme
    BNMD17 antikoerper, GPR48 antikoerper, 9130225G07 antikoerper, A330106J01Rik antikoerper, A930009A08Rik antikoerper, Gpr48 antikoerper, leucine rich repeat containing G protein-coupled receptor 4 antikoerper, leucine-rich repeat-containing G protein-coupled receptor 4 antikoerper, LGR4 antikoerper, Lgr4 antikoerper
    Hintergrund
    LGR4 (Leucine-rich repeat- containing G protein-coupled receptor 4, GPR48) belongs to the superfamily of G protein-coupled receptors (GPCRs). It is a 951 amino acid multi-pass membrane protein and has multiple N-terminal leucine-rich repeats, which are important for interaction with the glycoprotein ligands, and 7 transmembrane domains. LGR4 is highly expressed in the adult human pancreas but also with moderate levels of expression in placenta, kidney, brain and heart. LGR4 functions as an orphan receptor that may be involved in physiologic activities throughout the cell. It is overexpressed in various cancer types and is thought to enhance carcinoma invasiveness and metastasis, suggesting an important role in tumor progression.
    UniProt
    Q9BXB1
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