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GCNT1 Antikörper (AA 201-260)

GCNT1 Reaktivität: Human, Maus WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1714546
  • Target Alle GCNT1 Antikörper anzeigen
    GCNT1 (Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1))
    Bindungsspezifität
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 1
    AA 201-260
    Reaktivität
    Human, Maus
    Wirt
    • 36
    • 2
    • 1
    Kaninchen
    Klonalität
    • 39
    Polyklonal
    Konjugat
    • 14
    • 5
    • 5
    • 5
    • 5
    • 5
    Dieser GCNT1 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Cow,Sheep
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GCNT1
    Isotyp
    IgG
    Top Product
    Discover our top product GCNT1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    GCNT1 (Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1))
    Andere Bezeichnung
    GCNT1 (GCNT1 Produkte)
    Synonyme
    C2GNT antikoerper, C2GNT-L antikoerper, C2GNT1 antikoerper, G6NT antikoerper, NACGT2 antikoerper, NAGCT2 antikoerper, 5630400D21Rik antikoerper, B130048E03 antikoerper, C2 GlcNAcT antikoerper, IGnT antikoerper, core 2 GlcNAc-T antikoerper, glucosaminyl (N-acetyl) transferase 1, core 2 L homeolog antikoerper, glucosaminyl (N-acetyl) transferase 1, core 2 antikoerper, gcnt1.L antikoerper, GCNT1 antikoerper, Gcnt1 antikoerper
    Hintergrund

    Synonyms: 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase, Beta-1, Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase, C2GNT, C2GNT L, C2GNT1, C2GnTL, Core 2 branching enzyme, Core 2 GNT, Core 2-branching enzyme, Core2 GlcNAc transferase, Core2-GlcNAc-transferase, GCNT 1, GCNT 1, GCNT1, GCNT1_HUMAN, glucosaminyl N-acetyl transferase 1 core 2, NACGT2.

    Background: GCNT1 is expressed in a variety of cell types, including lymphocytes and mucin-producing cells. Specifically, GCNT1 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectins. Downregulation of Selectin ligand expression levels has been shown to inhibit tissue infiltration. Therefore, GCNT1 represents a potential drug target for the treatment of inflammatory disorders and other pathologies involving Selectins.

    Gen-ID
    2650
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