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PRKCSH Antikörper (AA 101-200) (HRP)

PRKCSH Reaktivität: Human WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN1712538
  • Target Alle PRKCSH Antikörper anzeigen
    PRKCSH (Protein Kinase C Substrate 80K-H (PRKCSH))
    Bindungsspezifität
    • 14
    • 9
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reaktivität
    • 59
    • 16
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 56
    • 3
    Kaninchen
    Klonalität
    • 57
    • 2
    Polyklonal
    Konjugat
    • 27
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PRKCSH Antikörper ist konjugiert mit HRP
    Applikation
    • 47
    • 22
    • 13
    • 13
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Cow,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Glucosidase 2 subunit beta
    Isotyp
    IgG
    Top Product
    Discover our top product PRKCSH Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    PRKCSH (Protein Kinase C Substrate 80K-H (PRKCSH))
    Andere Bezeichnung
    Glucosidase 2 subunit beta (PRKCSH Produkte)
    Synonyme
    AGE-R2 antikoerper, G19P1 antikoerper, PCLD antikoerper, PKCSH antikoerper, PLD1 antikoerper, 80K-H antikoerper, VASAP-60 antikoerper, zgc:55653 antikoerper, prkcsh antikoerper, MGC75615 antikoerper, MGC82696 antikoerper, PRKCSH antikoerper, protein kinase C substrate 80K-H antikoerper, protein kinase C substrate 80K-H L homeolog antikoerper, phospholipase D1 antikoerper, PRKCSH antikoerper, Prkcsh antikoerper, prkcsh antikoerper, prkcsh.L antikoerper, Bm1_42055 antikoerper, LOC100304710 antikoerper, LOC100526729 antikoerper, PLD1 antikoerper
    Hintergrund

    Synonyms: 80K-H protein, AGE-binding receptor 2, AGE-R2, G19P1, GLU2B_HUMAN, Glucosidase 2 subunit beta, Glucosidase II beta subunit, Glucosidase II subunit beta, Hepatocystin, PCLD, PKCSH, PLD1, PRKCSH, Protein kinase C substrate 60.1 kDa protein heavy chain, Protein kinase C substrate 80 Kda protein, Protein kinase C substrate 80K-H, Protein kinase C substrate, 80 Kda protein.

    Background: Trimming of glucoses from N-linked core glycans on newly synthesized glycoproteins occurs sequentially through the action of Glucosidases I and II in the endoplasmic reticulum (ER). Glucosidase II is an ER-localized enzyme that contains a and b subunits (Glucosidase IIa and Glucosidase IIb) which form a defined heterodimeric complex. Glucosidase IIa is the catalyitc core of the enzyme and can function independently of the b subunit. The sequence of Glucosidase IIb encodes protein rich in glutamic and aspartic acid with a putative ER retention signal (HDEL) at the C-terminus. The phosphorylated form of Glucosidase IIb is localized in the plasma membrane and is highly expressed in FGF-stimulated fibroblasts and epidermal carcinoma cells. Glucosidase IIb was first purified from a human carcinoma cell line as a potential substrate for protein kinase C. Through the HDEL signal at the C-terminus, Glucosidase IIb retains the complete complex in the ER.

    Gen-ID
    5589
    Pathways
    Cellular Glucan Metabolic Process, Methionine Biosynthetic Process
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