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CDX4 Antikörper (AA 185-284) (HRP)

CDX4 Reaktivität: Human ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN1712508
  • Target Alle CDX4 Produkte
    CDX4 (Caudal Type Homeobox 4 (CDX4))
    Bindungsspezifität
    • 14
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 185-284
    Reaktivität
    • 42
    • 16
    • 11
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 40
    • 5
    Kaninchen
    Klonalität
    • 40
    • 5
    Polyklonal
    Konjugat
    • 21
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CDX4 Antikörper ist konjugiert mit HRP
    Applikation
    • 20
    • 17
    • 13
    • 13
    • 7
    • 5
    • 2
    • 2
    • 2
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CDX4
    Isotyp
    IgG
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CDX4 (Caudal Type Homeobox 4 (CDX4))
    Andere Bezeichnung
    CDX4 (CDX4 Produkte)
    Synonyme
    Xcad3 antikoerper, Xcad-3 antikoerper, Xtcad3 antikoerper, MGC68909 antikoerper, MGC130769 antikoerper, CDXB antikoerper, CDX4 antikoerper, CHUNP6923 antikoerper, cad1 antikoerper, cb546 antikoerper, cdx1 antikoerper, id:ibd1215 antikoerper, id:ibd2812 antikoerper, id:ibd5107 antikoerper, kgg antikoerper, kugelig antikoerper, Cdx-3 antikoerper, Cdx-4 antikoerper, Cdx3 antikoerper, RGD1561529 antikoerper, cad3 antikoerper, cdx4 antikoerper, caudal type homeobox 4 antikoerper, caudal type homeo box 4 antikoerper, caudal type homeobox 4 L homeolog antikoerper, CDX4 antikoerper, cdx4 antikoerper, Cdx4 antikoerper, cdx4.L antikoerper
    Hintergrund

    Synonyms: Caudal-type homeobox protein 4, CDX4, CDX4_HUMAN, Homeobox protein CDX-4.

    Background: Cdx1, Cdx2 and Cdx4 are members of the caudal-type homeobox family of genes, which are homologs of the Drosophila caudal? gene required for anterior-posterior regional identity. The proteins encoded by these genes are transcription factors which play an important role in development by regulating the expression of Hox genes. Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. Cdx4 is a major positive regulator of the expression of all Hox family members. Due to its critical role as a regulator, Cdx4 is a direct target of the canonical Wnt pathway. The loss of Cdx4 can result in the development of an expanded hindbrain, while the overexpression of Cdx4 may cause the hindbrain to lose its distinct segmental features and resemble the spinal cord.

    Gen-ID
    1046
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