RRM2 Antikörper (AA 151-250) (HRP)
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- Target Alle RRM2 Antikörper anzeigen
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
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Bindungsspezifität
- AA 151-250
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RRM2 Antikörper ist konjugiert mit HRP
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human RRM2
- Isotyp
- IgG
- Top Product
- Discover our top product RRM2 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handhabung
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
- Andere Bezeichnung
- RRM2 (RRM2 Produkte)
- Synonyme
- R2 antikoerper, RR2 antikoerper, RR2M antikoerper, AA407299 antikoerper, rrm2 antikoerper, rr2m antikoerper, cb111 antikoerper, chunp6884 antikoerper, r2 antikoerper, ribonucleotide reductase regulatory subunit M2 antikoerper, ribonucleotide reductase M2 antikoerper, ribonucleotide reductase M2, gene 2 L homeolog antikoerper, ribonucleotide reductase M2, gene 1 antikoerper, ribonucleotide reductase M2 polypeptide antikoerper, RRM2 antikoerper, Rrm2 antikoerper, rrm2.2.L antikoerper, rrm2.1 antikoerper, rrm2 antikoerper
- Hintergrund
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Synonyms: R2, Ribonucleoside-diphosphate reductase subunit M2, Ribonucleotide reductase M2 subunit, Ribonucleotide reductase small chain, Ribonucleotide reductase small subunit, RIR2_HUMAN, RR2, RR2M, RRM2.
Background: Ribonucleotide reductase is essential for the production and maintenance of the level of deoxyribonucleoside triphosphates (dNTPs) required for DNA synthesis. It is an enzymatic complex consisting of two nonidentical subunits, R1 and R2, which are inactive separately. R2, the smaller subunit, is localized to the cytoplasm. R2 is the limiting factor of the catalytic activity of the ribonucleotide reductase enzymatic complex. R2 expression is strictly correlated to the S-phase of the cell cycle, whereas R1 remains constant throughout all phases of the cell cycle. While R2 seems to be involved solely in the maintenance of dNTPs for DNA replication, a similar protein, p53R2, has been shown to be responsible for the production of dNTPs in response to DNA damage.
- Gen-ID
- 6241
- Pathways
- Mitotic G1-G1/S Phases
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