HES7 Antikörper (AA 21-100) (HRP)

Produktnummer ABIN1712345

Produktdetails anti-HES7 Antikörper (HRP)

Target: HES7 (Hairy and Enhancer of Split 7 (HES7))

Bindungsspezifität: AA 21-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HES7 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HES7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HES7

Target: HES7 (Hairy and Enhancer of Split 7 (HES7))

Andere Bezeichnung: HES7 (HES7 Produkte)

Synonyme: SCDO4 antikoerper, bHLHb37 antikoerper, hes family bHLH transcription factor 7 antikoerper, hairy and enhancer of split 7 (Drosophila) antikoerper, HES7 antikoerper, Hes7 antikoerper

Hintergrund:

Synonyms: bHLH factor Hes7, bHLHb37, Class B basic helix loop helix protein 37, Class B basic helix-loop-helix protein 37, hairy and enhancer of split 7, Hes7, HES7_HUMAN, hHes7, SCDO4, Transcription factor HES 7, Transcription factor HES-7.

Background: HES7 is a 225 amino acid transcriptional repressor protein. Localized to the nucleus, HES7 represses transcription of N box- and E box-containing promoters. HES7, along with family member HES1, is thought to cooperatively regulate somite formation in the presomitic mesoderm. HES7 may also be essential for coordinated somite segmentation by acting as a segmentation clock. HES7 contains one basic helix-loop-helix (bHLH) domain and one Orange domain. Mutations in HES7 have been found to cause spondylocostal dysostosis, an autosomal recessive disorder characterized by deformities of the chest and spine.

Gen-ID: 84667