CYP51A1 Antikörper (AA 411-503) (HRP)

Produktnummer ABIN1712236

Produktdetails anti-CYP51A1 Antikörper (HRP)

Target: CYP51A1 (Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 (CYP51A1))

Bindungsspezifität: AA 411-503

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP51A1 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CYP51A1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CYP51A1

Target: CYP51A1 (Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 (CYP51A1))

Andere Bezeichnung: CYP51A1 (CYP51A1 Produkte)

Synonyme: CP51 antikoerper, CYP51 antikoerper, CYPL1 antikoerper, LDM antikoerper, P450-14DM antikoerper, P450L1 antikoerper, cyp51a1 antikoerper, cytochrome P450 family 51 subfamily A member 1 antikoerper, cytochrome P450, family 51, subfamily A, polypeptide 1 antikoerper, cytochrome P450 family 51 subfamily A member 1 L homeolog antikoerper, CYP51A1 antikoerper, cyp51a1 antikoerper, cyp51a1.L antikoerper

Hintergrund:

Synonyms: Lanosterol 14-alpha demethylase, LDM, CYPLI, Cytochrome P450 51A1, Cytochrome P450-14DM, Cytochrome P45014DM, Cytochrome P450LI, Sterol 14-alpha demethylase, CP51A_HUMAN.

Background: CYP51A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.

Gen-ID: 1595