CYP26A1 Antikörper (AA 101-200) (HRP)

Produktnummer ABIN1712235

Produktdetails anti-CYP26A1 Antikörper (HRP)

Target: CYP26A1 (Cytochrome P450, Family 26, Subfamily A, Polypeptide 1 (CYP26A1))

Bindungsspezifität: AA 101-200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP26A1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CYP26A1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CYP26A1

Target: CYP26A1 (Cytochrome P450, Family 26, Subfamily A, Polypeptide 1 (CYP26A1))

Andere Bezeichnung: CYP26A1 (CYP26A1 Produkte)

Synonyme: CP26 antikoerper, CYP26 antikoerper, P450RAI antikoerper, P450RAI1 antikoerper, Cyp26 antikoerper, P450RA antikoerper, RAH antikoerper, RACE antikoerper, XCYP26A1 antikoerper, cyp26 antikoerper, xCYP26 antikoerper, cp26 antikoerper, p450rai antikoerper, p450rai1 antikoerper, CYP26A antikoerper, cb24 antikoerper, id:ibd5061 antikoerper, wu:fb81e05 antikoerper, cytochrome P450 family 26 subfamily A member 1 antikoerper, cytochrome P450, family 26, subfamily a, polypeptide 1 antikoerper, cytochrome P450 family 26 subfamily A member 1 S homeolog antikoerper, cytochrome P450 family 26 subfamily A member 1 L homeolog antikoerper, cytochrome P450, family 26, subfamily A, polypeptide 1 antikoerper, CYP26A1 antikoerper, Cyp26a1 antikoerper, cyp26a1.S antikoerper, cyp26a1.L antikoerper, cyp26a1 antikoerper

Hintergrund:

Synonyms: CP26, CP26A_HUMAN, CYP26, CYP26A 1, cyp26a1, Cytochrome P450 26A1, Cytochrome P450 family 26 subfamily A polypeptide 1, Cytochrome P450 retinoic acid-inactivating 1, cytochrome P450, family 26, subfamily A, polypeptide 1, cytochrome P450, subfamily XXVIA, polypeptide 1, Cytochrome P450RAI, hP450RAI, OTTHUMP00000020102, OTTHUMP00000020103, P450, P450 retinoic acid inactivating 1, P450RAI, P450RAI1, Retinoic acid 4 hydroxylase, Retinoic acid 4-hydroxylase, Retinoic acid metabolizing cytochrome, Retinoic acid-metabolizing cytochrome.

Background: The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP26A1 is a major retinoic acid catabolic enzyme. CYP26A1 plays an important role in protecting tailbud tissues from inappropriate exposure to retinoic acid. CYP26A1 transcription is epigenetically regulated by nuclear retinoic acid receptor 2. Mutations in the gene encoding for CYP26A1 are associated with caudal agenesis and spina bifida, imperforate anus, agenesis of the caudal portions of the digestive and urogenital tracts, and malformed lumbosacral skeletal elements. CYP26A1 is upregulated in adenomatous polyposis coli mouse adenomas, human FAP adenomas, human sporadic colon carcinomas, and in the intestine of adenomatous polyposis coli (apcmcr) mutant zebrafish embryos.

Gen-ID: 1592

Pathways: Retinoic Acid Receptor Signaling Pathway, Monocarboxylic Acid Catabolic Process