ABCB7 Antikörper (AA 201-300) (HRP)

Produktnummer ABIN1712102

Produktdetails anti-ABCB7 Antikörper (HRP)

Target: ABCB7 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))

Bindungsspezifität: AA 201-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCB7 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ABCB7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ABCB7

Target: ABCB7 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))

Andere Bezeichnung: ABCB7 (ABCB7 Produkte)

Synonyme: CG7955 antikoerper, Dmel\\CG7955 antikoerper, dABCB7 antikoerper, GB11034 antikoerper, ABCB7 antikoerper, fc20c02 antikoerper, wu:fc20c02 antikoerper, ABC7 antikoerper, ASAT antikoerper, Atm1p antikoerper, EST140535 antikoerper, AA517758 antikoerper, AU019072 antikoerper, Abc7 antikoerper, ATP binding cassette subfamily B member 7 antikoerper, ATP-binding cassette sub-family B member 7, mitochondrial antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 7 antikoerper, ATP-binding cassette sub-family B member 7, mitochondrial-like antikoerper, ABCB7 antikoerper, LOC412749 antikoerper, abcb7 antikoerper, LOC100367778 antikoerper, LOC100467128 antikoerper, Abcb7 antikoerper

Hintergrund:

Synonyms: ABC transporter 7 protein, ABC7, Abcb7, ABCB7_HUMAN, ASAT, Atm1p, ATP binding cassette 7, ATP binding cassette sub family B MDR/TAP member 7, ATP binding cassette sub family B member 7, ATP binding cassette sub family B member 7 mitochondrial, ATP binding cassette transporter 7, ATP-binding cassette sub-family B member 7, ATP-binding cassette transporter 7, EST140535, MDR7, mitochondrial, Multidrug resistance protein 7, P-glycoprotein 7, PGP7.

Background: The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters, ABCD14 that are known to be present in the human peroxisome membrane (1). All four proteins are ABC half-transporters, which dimerize to form an active transporter (1). A mutation in the ABCD1 causes X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder which affects lipid storage (2,3). ABCD2 in mouse, is expressed at high levels in the brain and adrenal organs, which are adversely affected in X-ALD (4). The peroxisomal membrane comprises 2 quantitatively major proteins, PMP22 and ABCD3 (5). ABCD3 is associated with irregularly shaped vesicles which may be defective peroxisomes or peroxisome precursors (5). ABCD4 localizes to peroxisomes (1). The genes which encode ABCD14 map to human chromosome Xq28, 12q11-q12, 1p22-p21 and 14q24.3, respectively (3,68). ABCB7 is a half-transporter involved in the transport of heme from the mitochondria to the cytosol and maps to human chromosome Xq13.1-q13.3 (9).

Gen-ID: 22

Pathways: Transition Metal Ion Homeostasis