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CEP57 Antikörper (AA 51-150) (HRP)

CEP57 Reaktivität: Human ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN1711260
  • Target Alle CEP57 Antikörper anzeigen
    CEP57 (Centrosomal Protein 57kDa (CEP57))
    Bindungsspezifität
    • 14
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 51-150
    Reaktivität
    • 44
    • 3
    • 2
    • 1
    Human
    Wirt
    • 40
    • 4
    Kaninchen
    Klonalität
    • 43
    • 1
    Polyklonal
    Konjugat
    • 21
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CEP57 Antikörper ist konjugiert mit HRP
    Applikation
    • 29
    • 24
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CEP57
    Isotyp
    IgG
    Top Product
    Discover our top product CEP57 Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CEP57 (Centrosomal Protein 57kDa (CEP57))
    Andere Bezeichnung
    CEP57 (CEP57 Produkte)
    Synonyme
    3110002L15RIK antikoerper, CEP57 antikoerper, cep57r antikoerper, xCep57 antikoerper, c6orf182 antikoerper, 3110002l15rik antikoerper, RGD1309884 antikoerper, 3110002L15Rik antikoerper, 4921510P06Rik antikoerper, 4931428M20Rik antikoerper, AI467480 antikoerper, Tsp57 antikoerper, mKIAA0092 antikoerper, MVA2 antikoerper, PIG8 antikoerper, TSP57 antikoerper, centrosomal protein 57 antikoerper, centrosomal protein 57kDa-like 1 antikoerper, CEP57 antikoerper, cep57l1 antikoerper, Cep57 antikoerper
    Hintergrund

    Synonyms: Centrosomal protein 57 kDa, Centrosomal protein of 57 kDa, Cep57, Cep57 protein, CEP57_HUMAN, FGF2 interacting protein, FGF2-interacting protein, KIAA0092, MVA2, PIG8, proliferation inducing protein 8, Testis specic protein 57, Testis-specic protein 57, Translokin, TSP57.

    Background: CEP57 (centrosomal protein 57 kDa), also known as PIG8, TSP57 or Translokin, is a 500 amino acid protein that localizes to both the nucleus and the cytoplasm, specifically associating with microtubules at the centrosome. Expressed ubiquitously, CEP57 exists as a homodimer that functions to mediate the mitogenic activity and nuclear translocation of FGF-2, an internalized growth factor, thereby regulating FGF-2 signaling pathways. Additionally, CEP57 is thought to play a role in spermatogenesis, possibly via the indirect regulation of gene expression. Human CEP57 shares 88 % sequence identity with its mouse and bovine orthologs, suggesting a highly conserved role between species. Multiple isoforms of CEP57 exist due to alternative splicing events.

    Pathways
    M Phase, Maintenance of Protein Location, Protein targeting to Nucleus, Growth Factor Binding
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